Quantification of sedimented triamcinolone for intravitreal injection.

Purpose: To develop a practical method to concentrate triamcinolone acetonide for intravitreal injection.

Methods: A protocol using sedimentation was developed to increase the concentration of triamcinolone acetonide in a 0.1 mL dose.

Reproducibility of quantitative optical coherence tomography subanalysis in neovascular age-related macular degeneration.

Purpose: To determine the intergrader reproducibility for computer-assisted grading of optical coherence tomography (OCT) images in eyes with neovascular age-related macular degeneration (AMD), by using a standardized grading procedure.

Methods: Sixty OCT image sets (of six radial lines each) were independently analyzed by two graders using validated custom software (OCTOR) to draw boundaries manually on OCT B-scans. Spaces delineated by these boundaries included retina, subretinal fluid, subretinal tissue, and pigment epithelial detachments (PEDs).