Publications by authors named "Jerry O Conway"
Article Synopsis
- There are 7 known serotypes of botulinum neurotoxin (BoNT), and the development of specific immunoassays is complicated by the presence of cross-reactive non-neutralizing immunoglobulins.
- Researchers used recombinant antibody technology to create highly specific single domain antibodies (sdAb) from a llama immunized with all 7 serotypes of BoNT, achieving sensitive detection of the toxins in various samples.
- The study indicates that some sdAb not only identify toxins but also possess the potential to neutralize their effects, making them promising tools for both research and potential therapeutic applications.
