Publications by authors named "Jerrold Leikin"
Clin Toxicol (Phila)
August 2023
Article Synopsis
- Intravenous lipid emulsion has been proposed as a potential antidote for toxic drug overdoses based on the "lipid sink" theory, which suggests it can help sequester lipophilic drugs in the bloodstream.
- The study analyzed 134 cases from a toxicology registry to see if the survival rate after lipid therapy was related to the lipophilicity of the intoxicants involved.
- Results showed that 80.6% of patients survived, but there was no significant link between the intoxicant's lipophilicity and survival; however, systolic blood pressure improved for both groups after treatment.
