Conjunctival lichen planus simulating ocular surface squamous neoplasia.

Purpose: To describe the history and clinical presentation of a case of conjunctival lichen planus simulating ocular surface squamous neoplasia (OSSN).

Methods: A 32-year-old Hispanic man presented with a 6-month history of worsening foreign body sensation, localized conjunctival hyperemia, and a progressively enlarging "bump" located in the temporal aspect of his right eye. The patient denied any prior ocular trauma or surgery to the affected eye.

Incidence of rainbow glare after laser in situ keratomileusis flap creation with a 60 kHz femtosecond laser.

Purpose: To report the incidence of and factors associated with rainbow glare after laser in situ keratomileusis (LASIK) flap creation with a 60 kHz femtosecond laser.

Setting: Department of Refractive Surgery, Cleveland Clinic Cole Eye Institute, Cleveland, Ohio, USA.

Methods: Consecutive patients having LASIK by the same surgeon were questioned during postoperative examinations or by telephone about postoperative rainbow glare (radiating colors around a white light at night).

Tracking difficulties after femtosecond laser flap creation with the LADARVision excimer laser system.

Purpose: To describe a series of myopic patients in whom a LASIK flap was created with the IntraLase femtosecond laser. The LADARVision (Alcon Laboratories Inc) tracking system failed and resulted in postponement of surgery.

Methods: Five myopic Asian patients with darkly pigmented irides underwent bilateral superior hinge flap creation with three different femtosecond laser (IntraLase Corp) pulse frequencies: 15, 30, and 60 kHz.

Treatment of multidrug-resistant Flavobacterium indologenes keratitis with trimethoprim-sulfamethoxazole.

Purpose: To describe the history, clinical presentation, and successful medical management of a case of multidrug-resistant Flavobacterium indologenes keratitis.

Methods: An 83-year-old pseudophakic female presented with a 2-day history of decreased visual acuity, light sensitivity and dull ocular pain in her right eye. Two weeks before presentation, the patient had been treated for a red eye with combination topical loteprednol etabonate (0.

Comparative study of riboflavin-UVA cross-linking and "flash-linking" using surface wave elastometry.

Purpose: To investigate comparative stiffness values in porcine corneas after standard cross-linking and a new, rapid method of cross-linking (flash-linking) using surface wave elastometry.

Methods: Ten porcine eyes were treated using an ultraviolet A (UVA) double diode light source with a wavelength of 370 nm and delivering an irradiance of 4.2 mW/cm2 at a distance of 1.

Staged intrastromal delivery of riboflavin with UVA cross-linking in advanced bullous keratopathy: laboratory investigation and first clinical case.

Purpose: To evaluate the safety and efficacy of staged ultraviolet A (UVA) cross-linking following intrastromal 0.1% riboflavin administration in eyes with advanced corneal edema.

Methods: Ten eye bank corneas divided in two groups (n = 5) were placed on a pressurized artificial anterior chamber following Descemet's membrane stripping.

Posttraumatic Stenotrophomonas maltophilia infectious scleritis.

Purpose: To describe the history, clinical presentation, and successful surgical and antibiotic management of a case of posttraumatic infectious scleritis secondary to Stenotrophomonas maltophilia.

Methods: A 51-year-old white man presented with worsening light sensitivity, localized conjunctival hyperemia, and a painful scleral nodule in his right eye that developed over a period of 1 month after minor ocular trauma. The patient was treated by his referring ophthalmologist for "episcleritis" with fluorometholone 0.

Change in head posture and character of nystagmus in a patient with neurological upbeat nystagmus.

Purpose: To report a case of a patient with chin-up head posture and presumed congenital toxoplasmosis chorioretinal scars, who had a change in the character of the nystagmus and therefore the head posture following treatment for a neurological upbeat nystagmus.

Case Report: A 5 month old female presented with a chin up head posture and upbeat nystagmus. Magnetic resonance imaging of the brain revealed an arachnoid cyst in the area of the pineal gland.

Necrotizing nocardial scleritis after combined penetrating keratoplasty and phacoemulsification with intraocular lens implantation: a case report and review of the literature.

We report the history and clinical presentation of an 88-year-old female with Fuchs dystrophy who developed an acute anterior necrotizing scleritis in her left eye 23 months after an uncomplicated combined penetrating keratoplasty and phacoemulsification with intraocular lens implantation which progressed to slceral perforation with uveal prolapses. The patient underwent a complete systemic work-up for both autoimmune and infectious causes of scleritis. Surgical specimens of the area of scleral perforation were sent for histology and microbiologic studies.

How might corneal elasticity help us understand diabetes and intraocular pressure?

Purpose: To determine how changes in corneal elasticity/stiffness might influence intraocular pressure (IOP) readings in diabetic patients.

Methods: A systematic review of the literature was performed to understand the conflicting relationship between diabetes, elevated IOP, and glaucoma progression.

Results: Diabetic patients have been found to have statistically significant higher IOP readings in some population-based studies compared to non-diabetics.

Rapid resolution of topiramate-induced angle-closure glaucoma with methylprednisolone and mannitol.

Purpose: Topiramate-induced angle-closure glaucoma (TiACG) is believed to be related to its sulfonamide moiety. Although the exact mechanism is unknown, the time course and constellation of symptoms are consistent with a possible inflammatory pathophysiologic condition.

Design: Interventional case report.

Bacillus megaterium delayed onset lamellar keratitis after LASIK.

Purpose: To report the history and clinical presentation of a 23-year-old man who developed delayed onset lamellar keratitis in his right eye 2 weeks after uneventful LASIK for correction of myopia.

Methods: Initial clinical presentation suggested an infectious etiology, which led to therapeutic elevation of the LASIK flap and further microbiologic investigation with bacterial cultures.

Results: Bacterial cultures revealed Bacillus megaterium, which was sensitive to all antibiotics against which it was tested.

Is intraocular pressure in the early postoperative period predictive of antimetabolite-augmented filtration surgery success?

Purpose: To determine whether intraocular pressure (IOP) in the early postoperative period after trabeculectomy or combined phacoemulsification-trabeculectomy, augmented with antimetabolite, correlates with IOP at one year in surgeries considered to be successful at that time point.

Design: Retrospective case series.

Methods: A chart review of antimetabolite-augmented surgical procedures done by DJG and JBS between January 1994 and November 2000 identified 82 primary or secondary trabeculectomies and 53 combined phacoemulsification-trabeculectomies with at least one year of follow-up.

Mycobacterium chelonae-Mycobacterium abscessus complex clear corneal wound infection with recurrent hypopyon and perforation after phacoemulsification and intraocular lens implantation.

We report a clear corneal wound infection occurring in a 74-year-old man caused by a member of the Mycobacterium chelonae-Mycobacterium abscessus complex, presenting as crystalline keratopathy with recurrent hypopyon. This led to perforation after phacoemulsification with posterior chamber intraocular lens implantation. Only after corneal biopsy of the incision was the causative organism isolated and found to be sensitive to clarithromycin and ciprofloxacin.

The effect of laser iridotomy on the anterior segment anatomy of patients with plateau iris configuration.

Purpose: To determine if laser iridotomy altered the anterior segment anatomy of patients with plateau iris configuration.

Methods: Twenty eyes of 9 female and 1 male patients were imaged using an ultrasound biomicroscope within 19 weeks before and 52 weeks after laser iridotomy. Measurements obtained included the anterior chamber depth (ACD), trabecular-ciliary process distance (TCPD), iris thickness (IT), angle opening distance at 500 micrometers (AOD), iridozonular distance (IZD), and trabecular-iris angle (TIA).

Ultrasound biomicroscopy of the rat eye: effects of cholinergic and anticholinergic agents.

Background: Over the past few years the rat has gained prominence as an animal model for the study of glaucoma. However, no systematic study of the angle structures and the effects of medications on angle anatomy in the rat has been reported to date. We investigated the normal rat anterior segment anatomy in vivo using ultrasound biomicroscopy (UBM) and determined the effect of both cholinergic and anticholinergic medications on angle structures.

Cytoarchitecture of the retinal ganglion cells in the rat.

Purpose: To determine the number and cytoarchitecture of retinal ganglion cells (RGCs) in the female Wistar rat, by using a newly devised procedure for rapid RGC counting in the entire retina that avoids assumptions about RGC spatial arrangement.

Methods: RGCs of normal female Wistar rats were retrogradely labeled with a fluorescent tracer. Automated counting was accomplished by applying standard imaging software to analysis of all labeled cells in retinal flatmounts.