Synopsis of recent research by authors named "Jerome Daanen"
- Jerome Daanen's research primarily focuses on the synthesis and pharmacology of transient receptor potential vanilloid (TRPV) antagonists, particularly TRPV1 and TRPV3, targeting their roles in pain sensation and thermoregulation.
- His studies reveal distinctive pharmacological properties of TRPV1 ligands that can lead to hyperthermic or hypothermic effects, providing insights into structural modifications for drug discovery aimed at minimizing side effects.
- Daanen's work has contributed to the identification of selective TRPV antagonists that effectively manage pain without causing significant alterations in body temperature, thereby advancing therapeutic strategies for pain management.