Publications by authors named "Jerome Bousier"
Article Synopsis
- Non-alcoholic fatty liver disease (NAFLD) can lead to serious complications, and this study aims to create a metabolomic map to understand the metabolic changes across different stages, including steatosis, NASH, and fibrosis.
- Researchers conducted mass spectrometry on serum samples from 627 patients to identify unique and common metabolites associated with each stage of the disease, discovering 15 metabolites linked to steatosis, 18 to NASH, and 15 to fibrosis, with 27 shared across all stages.
- The study's findings emphasize that the transition from F2 to F3 fibrosis represents a significant metabolic change in NAFLD progression, highlighting the role of metabolic stress and oxidative stress in disease development.
