[Endoscopic nasopharyngectomy, a newly developed surgical technique offering significant clinical benefits in the treatment of nasopharyngeal malignancies].

Advances in endoscopic techniques used in sinonasal and skull base surgery have also resulted in the development of endoscopic surgery for malignant tumours in the nasopharynx. The nasopharynx provides great challenges for any surgeon due to its location deep into the cranium  and its close proximity to sensitive structures such as the carotid artery, orbital structures, pituitary gland and the skull base itself. The internationally developed technique of endoscopic nasopharyngectomy has been a clinical treatment option available in Sweden for the past couple of years.

Serotonin, ATRX, and DAXX Expression in Pituitary Adenomas: Markers in the Differential Diagnosis of Neuroendocrine Tumors of the Sellar Region.

Differential diagnosis based on morphology and immunohistochemistry between a clinically nonfunctioning pituitary neuroendocrine tumor (NET)/pituitary adenoma and a primary or secondary NET of nonpituitary origin in the sellar region may be difficult. Serotonin, a frequently expressed marker in the NETs, has not been systematically evaluated in pituitary NETs. Although mutations in ATRX or DAXX have been reported in a significant proportion of pancreatic NETs, the mutational status of ATRX and DAXX and their possible pathogenetic role in pituitary NETs are unknown.