LPS differentially affects expression of CD14 and CCR2 in monocyte subsets of Post-STEMI patients with hyperglycemia.

Aims: Following ST-segment elevation myocardial infarction (STEMI), recruitment and activation of monocytes [classical (CD14CD16CCR2), intermediate (CD14CD16CCR2), non-classical (CD14CD16CCR2)] are needed for myocardial wound healing. Monocyte surface receptor CC chemokine receptor type 2 (CCR2) is responsible for monocyte chemotaxis to sites of inflammation and the lipopolysaccharide (LPS)-binding protein co-receptor, CD14, is involved in pro-inflammatory monocyte activation. The purpose of this investigation was to determine the effects of ex-vivo LPS activation on monocyte subset CD14 and CCR2 expression in post-STEMI individuals with normal and elevated random blood glucose.

Prevalence of Cardiovascular Diseases Among Breast Cancer Survivors: Findings From the NHANES 2003-2018.

Purpose: To examine the prevalence of cardiovascular diseases (CVD) among breast cancer (BC) survivors.

Design: Cross-sectional observational study using the data from the National Health and Nutrition Examination Survey (NHANES) 2003-2018.

Setting: United States (US).

Effect of Polymer Network Architecture, Enhancing Soft Materials Using Orthogonal Dynamic Bonds in an Interpenetrating Network.

Doubly dynamic polymer networks were synthesized with two distinct exchangeable cross-linkers. The first linker is highly dynamic and rapidly exchanging hydrogen bonded 2-ureido-4[1]-pyrimidinone (UPy) and the second is a thermoresponsive furan-maleimide Diels-Alder adduct (FMI). Two network architectures were considered: an interpenetrating network (IPN) where one network is cross-linked with the UPy linker and the other is cross-linked with the FMI linker, and a single network (SN) where both the UPy and FMI linkers are in the same single network.