Graphical comparison of surgeon outcomes for the audit of a national corneal transplant registry (OTAG study 32).

Purpose: To compare Kaplan-Meier survival curves and funnel plots for the audit of surgeon-specific corneal transplantation outcomes.

Methods: We obtained data on all patients with Fuchs endothelial dystrophy (FED) receiving a first corneal transplant in one eye between January 2012 and December 2017. We produced 2-year Kaplan-Meier graft survival curves to compare a simulated individual surgeon's graft survival rate to national pooled data.

Primary Myoepithelial Carcinoma of the Conjunctiva.

A 38-year-old female, otherwise fit and well, presented with a mass on her left medial bulbar conjunctiva that had been enlarging for several months. Examinations showed a fixed pinkish tumour, 9 mm in maximum extent, spanning from the plica to the medial limbus. The tumour was removed in toto.

Oral antivirals for preventing recurrent herpes simplex keratitis in people with corneal grafts.

Background: Ocular herpes is a viral infection of the eye caused by the herpes simplex virus (HSV), a double-stranded DNA virus. Corneal scarring caused by herpes simplex keratitis (HSK) is the leading infectious cause of penetrating corneal graft in high-income countries. Acyclovir is an antiviral drug known to have a protective effect against recurrences in herpetic eye disease.

Autofluorescence Signatures of Seven Pathogens: Preliminary in Vitro Investigations of a Potential Diagnostic for Acanthamoeba Keratitis.

Purpose: Acanthamoeba keratitis can cause devastating damage to the human cornea and is often difficult to diagnose by routine clinical methods. In this preliminary study, we investigated whether Acanthamoeba may be distinguished from other common corneal pathogens through its autofluorescence response. Although only a small number of pathogens were studied, the identification of a unique Acanthamoeba signature would indicate that autofluorescence spectroscopy as a diagnostic method merits further investigation.

A case of Phoma fungal keratitis in a contact lens user.

Fungi of the genus Phoma are common plant pathogens and saprophytes and are rarely pathogenic to animals.

Validation of a semi-automated computer-aided technique for quantifying corneal vascularisation and scarring.

Background/aims: To determine the validity and reproducibility of a semi-automated computer-aided method of quantifying corneal vascularisation and scarring.

Methods: Software for quantifying corneal vascularisation and scarring was devised and its validity was tested. Three masked clinicians viewed 20 corneal photographs and estimated the percentages of the cornea that were (a) scarred and (b) vascularised.

Progressive lenticular astigmatism in the clear lens.

We describe a case of progressive lenticular astigmatism in a 53-year-old man with a clear lens. The patient acquired 5 diopters of lenticular astigmatism in his right eye over an 18-month period. The visual acuity was reduced to 6/60.