A recurrent de novo missense mutation in COL1A1 causes osteogenesis imperfecta type II and preterm delivery in Normande cattle.

Background: Nine male and eight female calves born to a Normande artificial insemination bull named "Ly" were referred to the French National Observatory of Bovine Abnormalities for multiple fractures, shortened gestation, and stillbirth or perinatal mortality.

Results: Using Illumina BovineSNP50 array genotypes from affected calves and 84 half-sib controls, the associated locus was mapped to a 6.5-Mb interval on chromosome 19, assuming autosomal inheritance with germline mosaicism.

Usefulness of serum amyloid A for the diagnosis of pyelonephritis in cats: A prospective evaluation.

Background: The diagnosis of pyelonephritis in cats is challenging and development of a noninvasive and accurate biomarker is needed.

Hypotheses: Serum amyloid A (SAA) is increased in cats with pyelonephritis, but not in cats with other urinary tract diseases.

Animals: A cohort of 125 cats (149 observations).

Congenital Partial Colonic Agenesis in Dogs and Cats: Clinical, Biological, Diagnostic Imaging, Endoscopic and Histopathologic Characterization, a Retrospective Study.

Congenital diseases of the large intestine of dogs and cats have scarcely been reported and mostly include fistula, atresia or colonic duplication. Cases of partial colonic agenesis have rarely been described. The purpose of this study was to report a cohort of dogs and cats diagnosed with partial colonic agenesis.

Survey of factors affecting satisfaction and success of residents enrolled in European College of Veterinary Diagnostic Imaging (ECVDI) residency programs.

Several published studies have described the success and satisfaction of residents enrolled in human radiology training programs, however comparable studies for veterinary radiology residents are currently lacking. The purpose of this descriptive, survey study was to evaluate resident perceptions of the European College of Veterinary Diagnostic Imaging (ECVDI) residency training programs. A web-based survey was sent to all listed 114 ECVDI residents and received a 57.

Cats with idiopathic chronic rhinosinusitis that develop clinical signs before two years of age have more severe nasal conchal lysis, sinus malformation, and more severe inflammation on histological examination.

Objective: To evaluate the severity of sinonasal lesions on CT in cats with feline idiopathic chronic rhinosinusitis (FICR) comparing cats who developed the condition at a young age to those who developed it as an adult. And, to assess if CT findings correlate with histopathology.

Animals: 58 cats with FICR confirmed on histopathology.

Dynamic contrast-enhanced computed tomography perfusion parameters of canine suspected brain tumors at baseline and during radiotherapy might be different depending on tumor location but not associated with survival.

Introduction: Treatment of brain tumors in dogs can be associated with significant morbidity and reliable prognostic factors are lacking. Dynamic contrast-enhanced computed tomography (DCECT) can be used to assess tumor perfusion. The objectives of this study were to assess perfusion parameters and change in size of suspected brain tumors before and during radiotherapy (RT) depending on their location and find a potential correlation with survival.

Dynamic contrast-enhanced computed tomography in dogs with nasal tumors.

Background: Treatment of nasal tumors in dogs is associated with high morbidity and reliable prognostic factors are lacking. Dynamic contrast-enhanced computed tomography (DCECT) can be used to assess tumor perfusion.

Objectives: To assess perfusion parameters of nasal tumors (correlating with tumor type) before and during radiotherapy (RT) and find potential correlation with survival.

Dynamic contrast-enhanced computed tomography in 11 dogs with orofacial tumors.

Objective: Treatment of orofacial tumors in dogs is associated with high morbidity and reliable prognostic factors are lacking. Dynamic contrast-enhanced computed tomography (DCECT) can be used to assess tumor perfusion. The objectives of this study were to describe the perfusion parameters of different types of orofacial tumors and to describe the changes in perfusion parameters during radiotherapy (RT) in a subset of them.

Suspected spontaneous early hemorrhagic transformation of multiple ischemic strokes secondary to primary splenic torsion in a German Shepherd dog.

A 3-year-old female German Shepherd dog was presented with generalized tonic-clonic epileptic seizures, right-sided central vestibular syndrome, and right trigeminal nerve dysfunction. Acute lacunar ischemic strokes within both thalami, right side of the mesencephalon, left side of the myelencephalon, both sides of the cervical spinal cord, and acute hemorrhagic strokes within the rostral part of the right cerebellar hemisphere and right rostral colliculus were identified on magnetic resonance imaging. Additional evaluation identified multiple renal infarcts and complete splenic torsion, with entrapment of the left pancreatic lobe.

Prevalence of bronchial wall thickening and collapse in brachycephalic dogs with and without brachycephalic obstructive airway syndrome and in nonbrachycephalic dogs.

Objective: To assess the prevalence of bronchial wall thickening (BWT) and collapse in brachycephalic dogs with and without brachycephalic obstructive airway syndrome (BOAS) and in nonbrachycephalic dogs.

Animals: 85 dogs with no history of lower respiratory tract disease that underwent CT of the thorax.

Procedures: Electronical medical records for March 2011 through August 2019 were reviewed to identify brachycephalic dogs with BOAS (BOAS group) and brachycephalic dogs without BOAS (BDWB group) that did not have any evidence of lower respiratory tract disease and had undergone thoracic CT.

Imaging characteristics of thoracolumbar spinal stenosis due to articular process hyperplasia and degenerative joint disease in six large breed dogs.

Previous studies have reported evidence that thoracolumbar articular process hyperplasia and degenerative joint disease may be a cause of stenotic myelopathy in large breed dogs; however, detailed descriptions of imaging characteristics are currently lacking. The aim of this retrospective, multi-center, case series report was to describe imaging findings in six large breed dogs diagnosed with thoracolumbar articular process hyperplasia and degenerative joint disease causing vertebral canal stenosis. All dogs presented with progressive paraparesis, proprioceptive ataxia of the pelvic limbs, and neuroanatomical localization of T3-L3 myelopathy.

Imaging features of retroperitoneal extra-adrenal paragangliomas in 10 dogs.

Retroperitoneal paragangliomas are rare tumors of the neuroendocrine system. Only a few canine case reports are available with rare descriptions of their imaging features. The objectives of this multi-center, retrospective case series study were to describe the diagnostic imaging features of confirmed retroperitoneal paragangliomas and specify their location.

Imaging findings in 14 dogs and 3 cats with lobar emphysema.

Background: Lobar emphysema in dogs and cats is caused by bronchial collapse during expiration and subsequent air trapping. Congenital causes such as bronchial cartilage defects or acquired causes such as compressive neoplastic lesions have been reported. Morbidity results from hyperinflation of the affected lung lobe and compression of adjacent thoracic structures.

Clinical, CT, and ultrasonographic features of canine and feline pleural and peritoneal carcinomatosis and sarcomatosis.

Carcinomatosis and sarcomatosis describe the widespread dissemination of metastatic neoplastic cells throughout the body. Studies describing their clinical and imaging features in veterinary patients are limited. The objective of this retrospective, multicenter, cross-sectional study is to describe the clinical, ultrasonographic, and CT features of pleural and peritoneal carcinomatosis and sarcomatosis in dogs and cats to aid detection and differentiation of these lesions.

Clinical, computed tomographic and histopathological findings in two cats with pulmonary fibrosis of unknown aetiology.

Case Series Summary: Two cats were presented for further investigation of respiratory signs. One cat had a history of a cough and the other, tachypnoea. In each case, thoracic CT was performed, which revealed a generalised marked reticular pattern in the first cat and focal consolidation of the right caudal lung lobe in the second cat.

Safety of percutaneous ultrasound-guided fine-needle aspiration of adrenal lesions in dogs: Perception of the procedure by radiologists and presentation of 50 cases.

Background: Percutaneous ultrasound (US)-guided fine-needle aspiration (FNA) of adrenal gland lesions is controversial in veterinary medicine.

Objective: To evaluate the frequency and radiologists' perception of the risk of the procedure as well as determining the incidence of complications.

Methods: Retrospective study.

CT findings in five dogs with surgically confirmed colonic torsion.

Colonic torsion is a life-threatening condition that results in colonic ischemia, necrosis, perforation, sepsis, and eventual death. The aim of this multicenter, retrospective case series study was to describe the CT findings in dogs with surgically confirmed colonic torsion. Medical records were searched for dogs with surgically confirmed colonic torsion following abdominal CT.

Prevalence and clinical significance of the medullary rim sign identified on ultrasound of feline kidneys.

Objectives: The medullary rim sign (MRS) is an ultrasonographic (US) feature identified in normal and diseased feline kidneys. The prevalence and potential clinical significance of the MRS in a referral hospital cat population was investigated.

Methods: Retrospective case-control study.

Accuracy of and interobserver agreement regarding thoracic computed tomography for the diagnosis of chronic bronchitis in dogs.

OBJECTIVE To characterize CT findings in dogs with a presumptive diagnosis of chronic bronchitis, estimate the accuracy of thoracic CT for the diagnosis of chronic bronchitis in dogs, and determine interobserver agreement for this method. DESIGN Retrospective case-control and cross-sectional study. ANIMALS 26 dogs with confirmed chronic bronchitis and 20 control dogs with unremarkable results of thoracic CT and no recorded history of cough.

MRI findings of neuronal ceroid lipofuscinosis in a cat.

Case Summary: A 2-year-old male domestic shorthair cat presented to the University of Liverpool Small Animal Teaching Hospital with a 2 week history of altered mentation, blindness and focal epileptic seizures. MRI examination revealed generalised cerebral and cerebellar atrophy, diffuse T2-weighted hyperintensity of the white matter and meningeal thickening. Neuronal ceroid lipofuscinosis was confirmed on post-mortem examination.

Computed tomographic findings in three dogs naturally infected with Crenosoma vulpis.

Crenosoma vulpis is a nematode lungworm found in wild and domestic canids in some parts of North America and Europe. Reported radiographic findings are nonspecific and consist of a combination of bronchial and interstitial changes of variable severity. This retrospective, case series study aimed to describe thoracic computed tomographic (CT) findings for a group of dogs with confirmed crenosomosis.

Neoplastic pleural effusion and intrathoracic metastasis of a scapular osteosarcoma in a dog: a multidisciplinary integrated diagnostic approach.

A 10-year-old, female spayed mixed-breed or cross-bred dog was referred to the Small Animal Teaching Hospital of the University of Liverpool due to tachypnea, dyspnea, and pleural effusion not responding to diuretics and antibiotics. The chest was drained and cytology of the pleural fluid was consistent with a modified transudate with presence of atypical cells initially attributed to mesothelial hyperplasia and dysplasia. Computed tomography detected, in addition to the bilateral pleural effusion, diffuse pleural thickening, multiple pleural and pulmonary nodules, and a mineralized and lytic mass in the left scapula.

Ultrasonographic appearance of the major duodenal papilla in dogs without evidence of hepatobiliary, pancreatic, or gastrointestinal tract disease.

OBJECTIVE To determine the ultrasonographic appearance of the major duodenal papilla (MDP) in dogs without evidence of hepatobiliary, pancreatic, or gastrointestinal tract disease. ANIMALS 40 adult client-owned dogs examined because of conditions that did not include hepatobiliary, pancreatic, or gastrointestinal tract disease. PROCEDURES Ultrasonographic examination of the MDP was performed.