Publications by authors named "Jeremy J Peavey"
Introduction: Retinal vascular network changes may reflect the integrity of the cerebral microcirculation, and may be associated with cognitive impairment.
Methods: Associations of retinal vascular measures with cognitive function and MRI biomarkers were examined amongst Multi-Ethnic Study of Atherosclerosis (MESA) participants in North Carolina who had gradable retinal photographs at Exams 2 (2002 to 2004, n = 313) and 5 (2010 to 2012, n = 306), and detailed cognitive testing and MRI at Exam 6 (2016 to 2018).
Results: After adjustment for covariates and multiple comparisons, greater arteriolar fractal dimension (FD) at Exam 2 was associated with less isotropic free water of gray matter regions (β = -0.
Article Synopsis
- - The study investigates small extracellular vesicles (sEVs) derived from brain cells in blood to find potential biomarkers for Alzheimer's disease (AD) by analyzing microRNA (miRNA) levels in older adults with varying cognitive abilities.
- - Researchers isolated sEVs from participants with normal cognition, mild cognitive impairment (MCI), and AD, revealing that miRNA expression patterns significantly differentiated between these groups and correlated with brain imaging results.
- - The findings suggest that analyzing miRNAs in sEVs provides a promising, non-invasive blood-based method for detecting and monitoring Alzheimer's disease progression.
Objective: To investigate the impact of socioeconomic disadvantage and diabetic retinopathy severity on follow-up for vision care among people with diabetes mellitus (DM) residing in rural Vermont and northern New York State.
Methods: A retrospective chart review of people with DM who visited our academic eye clinic at least once between October 1, 2015, and March 31, 2016, was done. Of 1,466 unique patient visits, 500 were chosen for full chart review by simple random sampling.