Safety of intracranial electrodes in an MRI environment: a technical report.

Introduction: Intracranial electroencephalography (iEEG) involves placing intracranial electrodes to localise seizures in patients with medically refractory epilepsy. While magnetic resonance imaging (MRI) enables visualisation of electrodes within patient-specific anatomy, the safety of these electrodes must be confirmed prior to routine clinical utilisation. Therefore, the purpose of this study was to evaluate the safety of iEEG electrodes from a particular manufacturer in a 3.

Endoscopic ultrasound-directed transgastric ERCP (EDGE): A multicenter US study on long-term follow-up and fistula closure.

Endoscopic ultrasound-directed transgastric ERCP (EDGE) is a safe and efficacious procedure to treat pancreaticobiliary diseases in Roux-en-Y gastric bypass (RYGB). This multicenter study aimed to determine the long-term outcomes of EDGE focusing on fistula persistence rates and post-procedure weight change. Information about patients with Roux-en-Y gastric bypass anatomy who underwent EDGE between 2015 and 2021 from 10 institutions was captured in a registry.

Impacted gallstone within a cholecystoduodenal fistula: endoscopic laser lithotripsy to the rescue.

Video 1A large, impacted gallstone is treated unsuccessfully with electrohydraulic lithotripsy; however, fragmentation and removal is accomplished using endoscopic laser lithotripsy.

Comparing the Safety and Efficacy of Two Commercially Available Single-Use Duodenoscopes: A Multicenter Study.

Introduction: Single-use disposable duodenoscopes (SDD) have been developed to mitigate infectious risks related to reusable duodenoscopes. The aim of this study is to compare the safety and efficacy of the two available SDDs in the United States.

Methods: We conducted a comparative study of 2 SDD in consecutive ERCP procedures performed by expert endoscopists from 9 academic centers.

An examination of the Kuleshov effect using still photographs.

The goal of the present study was to examine whether the effect of visual context on the interpretation of facial expression from an actor's face could be produced using isolated photographic stills, instead of the typical dynamic film sequences used to demonstrate the effect. Two-photograph sequences consisting of a context photograph varying in pleasantness and a photograph of an actor's neutral face were presented. Participants performed a liking rating task for the context photograph (to ensure attention to the stimulus) and they performed three tasks for the face stimulus: labeling the emotion portrayed by the actor, rating valence, and rating arousal.

Learning and memory deficits in mice lacking protease activated receptor-1.

The roles of serine proteases and protease activated receptors have been extensively studied in coagulation, wound healing, inflammation, and neurodegeneration. More recently, serine proteases have been suggested to influence synaptic plasticity. In this context, we examined the role of protease activated receptor 1 (PAR1), which is activated following proteolytic cleavage by thrombin and plasmin, in emotionally motivated learning.

Subunit-specific mechanisms and proton sensitivity of NMDA receptor channel block.

We have compared the potencies of structurally distinct channel blockers at recombinant NR1/NR2A, NR1/NR2B, NR1/NR2C and NR1/NR2D receptors. The IC50 values varied with stereochemistry and subunit composition, suggesting that it may be possible to design subunit-selective channel blockers. For dizocilpine (MK-801), the differential potency of MK-801 stereoisomers determined at recombinant NMDA receptors was confirmed at native receptors in vitro and in vivo.