Publications by authors named "Jeremy B Provance"

Background: Shared medical decision making requires patients' understanding of their disease and its treatment options. Peripheral artery disease (PAD) is a condition for which preference-sensitive treatments are available, but for which little is known about patients' knowledge and treatment preferences as it relates to specific treatment goals.

Methods: In a prospective, multicenter registry that involved patients with PAD experiencing claudication, the PORTRAIT Knowledge and Preferences Survey was administered at 1 year.

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Background: Lack of guideline-directed medical therapy (GDMT) in patients undergoing peripheral vascular interventions (PVIs) may increase mortality and amputation risk.

Objectives: The authors sought to study the association between GDMT and mortality/amputation and to examine GDMT variability among providers and health systems.

Methods: We performed an observational study using patients in the Vascular Quality Initiative registry undergoing PVI between 2017 and 2018.

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Background: Antiplatelet monotherapy is recommended after infrainguinal lower extremity bypass (LEB). However, there is a paucity of high-quality data to guide therapy, and antiplatelet therapy is often prescribed in combination with anticoagulation. We therefore aimed to assess the variability in the use of antithrombotic therapy after infrainguinal LEB.

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Patients with critical limb ischemia (CLI) can undergo endovascular peripheral vascular intervention (PVI) to restore blood flow and decrease risk of amputation. As a potential indicator of quality for CLI care, we sought to describe 30-day major amputation rates following PVI. We also examined rate variability, and patient-level and site-level factors predicting amputations, using a national electronic health record (EHR) database.

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Article Synopsis
  • Guideline-directed medical therapy (GDMT) is crucial for improving outcomes in patients with critical limb ischemia (CLI), especially those with chronic kidney disease (CKD).
  • A study analyzed the prescription rates of GDMT for CLI patients undergoing peripheral vascular interventions, highlighting that those with CKD received lower rates of GDMT both before and after the procedure.
  • There was notable variability in GDMT delivery across different medical sites, indicating a need for better management strategies for patients, particularly those at higher risk for poor outcomes.
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Importance: Identifying modifiable risk factors, such as stress, that could inform the design of peripheral artery disease (PAD) management strategies is critical for reducing the risk of mortality. Few studies have examined the association of self-perceived stress with outcomes in patients with PAD.

Objective: To examine the association of high levels of self-perceived stress with mortality in patients with PAD.

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