Publications by authors named "Jeremy A W Gold"
An Update on Fungal Disease Outbreaks of Public Health Concern.
Infect Dis Clin North Am
December 2024
For this narrative review, we describe recent high-profile and severe outbreaks of emerging fungal infections, emphasizing lessons learned and opportunities to improve future prevention and response efforts. Several themes and challenges remain consistent across a diverse array of fungal outbreaks, including the multidisciplinary need for improved diagnostic testing to determine species and perform antifungal susceptibility testing, clinical awareness, and optimization of antifungal use. Recent outbreaks exemplify the growing promise of non-culture-based tools in identifying fungal outbreaks and improving responses, although access remains limited.
View Article and Find Full Text PDFPrescribing of clotrimazole-betamethasone dipropionate, a topical combination corticosteroid-antifungal product, for Medicare part D beneficiaries, United States, 2016-2022.
Antimicrob Steward Healthc Epidemiol
October 2024
Article Synopsis
In a commercial claims database analysis, <0.5% of patients with inflammatory bowel disease or rheumatoid arthritis developed an IFI within one year of initiating TNF-alpha therapy. Histoplasmosis was the most common IFI type.
View Article and Find Full Text PDFAntifungal-resistant dermatophyte infections have recently emerged as a global public health concern. A survey of US infectious diseases specialists found that only 65% had heard of this issue and just 39% knew how to obtain testing to determine resistance. Increased clinician awareness and access to testing for antifungal-resistant dermatophytosis are needed.
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- Pityriasis versicolor (PV) is a fungal skin infection most common in younger individuals, particularly in humid conditions and is linked to factors like hyperhidrosis.
- A case-control study using the All of Us Database identified 456 PV patients and 1368 controls, revealing that PV sufferers are typically younger, more often male, and have higher incidences of acne compared to controls.
- The findings suggest that acne may increase the risk of developing PV, while factors such as type 2 diabetes mellitus and older age may reduce it, indicating potential educational opportunities for physicians to inform acne patients about PV prevention strategies.
Article Synopsis
- * These infections are significant as they cause morbidity and stigma, and their occurrence may rise due to climate change and increased global travel.
- * U.S. dermatologists are crucial for early detection and treatment of these conditions, which can reduce complications and improve patient outcomes.
Article Synopsis
- * These diseases are linked to poverty and immunosuppression, particularly in the U.S. due to global migration, and have serious morbidity effects like disfigurement, disability, and mental health issues.
- * Effective management is challenging with low cure rates, highlighting the important role of dermatologists in early diagnosis and treatment to enhance patient outcomes.
In 2 large health insurance claims databases, cryptococcosis prevalence was 3.4 cases per 100 000 commercially insured patients and 6.5 per 100 000 Medicaid patients.
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- - Tinea capitis is a fungal infection of the scalp primarily affecting children but also seen in adults, with postmenopausal African American women at higher risk.
- - Adults living in crowded conditions or with weakened immune systems, particularly those in households with infected children, are more prone to this condition.
- - Diagnosis typically involves fungal cultures and trichoscopy, while treatment focuses on oral antifungals like griseofulvin and terbinafine; however, resistance to treatment is becoming a concern.
Article Synopsis
- Fungal infections are becoming more common because more people are at risk and climate change is affecting health.
- There are only a few types of antifungal medicines available, and they have problems like resistance from fungi and side effects that need close monitoring.
- Scientists are exploring new antifungal options, including inhaled treatments and ways to boost the immune system, to better fight these infections and understand issues like drug resistance.
In a nationally representative hospital discharge database, esophageal candidiasis-associated hospitalization rates per 100 000 population steadily declined from 17.0 (n = 52 698, 2010) to 12.9 (n = 42 355, 2020).
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