Role of magnetic resonance imaging before initial biopsy: comparison of magnetic resonance imaging-targeted and systematic biopsy for significant prostate cancer detection.

Objective: •To compare magnetic resonance imaging (MRI)-targeted biopsies with extended systematic biopsies for the detection of significant prostate cancer.

Methods: •In all, 555 consecutive patients with suspicion of prostate cancer had pre-biopsy dynamic contrast-enhanced 1.5-tesla (T) MRI with pelvic coil, 10-12 transrectal ultrasound-guided extended systematic biopsies plus two targeted biopsies at any MRI area suspicious for malignancy.

Current status of MRI for the diagnosis, staging and prognosis of prostate cancer: implications for focal therapy and active surveillance.

Purpose Of Review: To review the current status of MRI techniques in identification of organ-confined prostate cancer with a focus on their implication for focal therapy and active surveillance.

Recent Findings: MRI is currently focusing on intraprostatic prostate cancer identification and at 1.5T, it provides excellent imaging of the whole gland including the challenging anterior part.

[What is prostate cancer?].

Prostate cancer can be diagnosed by individual screening (digital examination and PSA assay at age > 50 y) when still localized and asymptomatic. The diagnosis is confirmed by staged biopsies and by magnetic resonance imaging (MRI) with targeted biopsies. A better knowledge of the natural history of prostate cancer, together with improvements in MRI, can help to predict the location, volume, local extension and prognosis prior to treatment.

Peripheral zone prostate cancers: location and intraprostatic patterns of spread at histopathology.

Background: To describe the precise location of peripheral zone (PZ) prostate cancers at various stages of development and to demonstrate their pattern of intraprostatic spread from their site of origin.

Methods: PZ cancers defined as cancers located in peripheral zone (PZ) including the anterolateral part of PZ, were identified from radical prostatectomy specimens. PZ cancers morphometric histopathological study included largest surface area, volume and spatial distribution.

[Gastric or duodenal metastases from clear cell renal cell carcinoma. Report of two cases and review of the literature].

Introduction: Gastric or duodenal metastases from clear cell renal cell carcinoma are exceptional. According to autopsy series, the incidence of gastrointestinal metastases is 0.06 to 4% for all cancers and 0.

[Management of locally advanced prostatic adenocarcinoma in France. OCTAVE observational survey].

Objective: To describe the management of patients with locally advanced prostate cancer in France and the changes in this management between 2000 and 2003.

Material And Methods: Observational survey on a sample of urologists and radiotherapists throughout France, comprising 2 aspects: a retrospective aspect (patients diagnosed and treated in 2000) and a prospective aspect (patients diagnosed in 2003 during the survey period). Eligible patients presented locally advanced prostate cancer (T3, biopsy pT3, T4, NO-N1-Nx, M0), not treated in the context of a therapeutic trial.