Effect of Six-Week Speed Endurance Training on Peripheral Fatigue.

(1) Speed endurance training (inducing a high blood lactate concentration) delays excitation-contraction coupling impairment, thus providing more space for high-frequency fatigue to occur in the early stage of maximal concentric actions. This study aimed to test the hypothesis that the maintenance type of speed endurance training may shift peripheral fatigue from low-frequency to high-frequency fatigue after the 15 s long Wingate test. (2) Six students of physical education performed the corresponding training for six weeks.

Traffic Density-Related Black Carbon Distribution: Impact of Wind in a Basin Town.

Black carbon is one of the riskiest particle matter pollutants that is harmful to human health. Although it has been increasingly investigated, factors that depend on black carbon distribution and concentration are still insufficiently researched. Variables, such as traffic density, wind speeds, and ground levels can lead to substantial variations of black carbon concentrations and potential exposure, which is even riskier for people living in less-airy sites.

Features influencing policy recommendations for the promotion of zero-emission vehicles in Slovenia, Spain, and Poland.

Abstract: To make society more sustainable, cleaner transportation technologies, such as zero-emission vehicles and sustainable mobility, are being investigated, promoted, and supported by different policy measures. The emphasis of this paper is determining the zero-emission vehicle features that can influence specific policy recommendations; this understanding can boost zero-emission vehicle use as a potential cleaner transportation technology among different consumer segments in different EU member states. A customer-oriented study of over 1500 Slovenians, Spaniards, and Poles revealed the most relevant zero-emission vehicle-purchasing features are: (a) vehicle price and (b) fuel economy.

Genotyping of BRCA1, BRCA2, p53, CDKN2A, MLH1 and MSH2 genes in a male patient with secondary breast cancer.

Background: Some tumour suppressor genes (BRCA2) and mismatch repair genes (MSH2, MLH1) are correlated with an increased risk for male breast cancer.

Case Report: Our patient developed secondary breast cancer after the treatment for Hodgkin's disease in childhood. DNA was isolated from the patients' blood and screened for mutations, polymorphisms and variants in BRCA1, BRCA2, p53, CDKN2A, MLH1 and MSH2 genes.

Late somatic sequelae after treatment of childhood cancer in Slovenia.

Background: This is a long-term follow-up clinical study of adolescents and adults, survivors of childhood cancer. We evaluate and analyze the late somatic sequelae of childhood cancer treatment. Many such studies are susceptible to a strong selection bias, i.

Slovenian practice story: 10 years of e-counselling service for teenagers.

This is Me is the largest youth counseling web portal in Slovenia, providing teens with a friendly, simple, fast, free, anonymous and efficient public access to expert information and problem-solving assistance. Network of web counselors includes 38 experts (medical specialists, psychologists, social pedagogues, social workers, and teachers), who are volunteers from 12 different institutions. In the course of ten years, experts have answered almost 21,000 questions about dilemmas and problems faced by teens.

Gonadal function in patients treated for Hodgkin's disease in childhood.

Background: The long-term survival of patients treated for Hodgkin`s disease (HD) in childhood is high and the chief concern is now being directed toward the late effects of the treatment, including the endocrine dysfunction. PATIENTS AND METHODS.: Testicular and ovarian functions were assessed in 64 long term survivors (24 females, 40 males) treated for HD in childhood in Slovenia between 1972 and 1994.

Prognostic value of immunohistochemistry in the Ewing's sarcoma family of tumors.

Background: The expressions of different markers have been immunohistochemically studied in various types of the Ewing's sarcoma family of tumors, especially for diagnostic purposes. However, little is known about their prognostic value in combination with the clinicopathological data of such patients.

Material/methods: This retrospective study investigated the immunohistochemical expressions of NSE, TdT, EMA, S-100, CK MNF116, p53, bcl-2, CD99, and CD117 on formalin-fixed paraffin-embedded material of 72 patients (age range: 2-59 years) with various types of Ewing's sarcoma family of tumors using the tissue microarray method.

Trends in survival after childhood cancer in Slovenia between 1957 and 2007.

Objectives: To evaluate childhood cancer survival in Slovenia, to provide results comparable to ACCIS studies, and to study the effect of recorded variables on 5-year survival.

Methods: The data are registry-based and present a unique collection in terms of control and homogeneity. Survival was explored using Kaplan-Meier estimates and the Cox model.

Cardiac damage after treatment of childhood cancer: a long-term follow-up.

Background: With improved childhood cancer cure rate, long term sequelae are becoming an important factor of quality of life. Signs of cardiovascular disease are frequently found in long term survivors of cancer. Cardiac damage may be related to irradiation and chemotherapy.

The influence of strength-endurance training on the oxygenation of isometrically contracted forearm muscles.

Ice-climbers frequently use the squeezing of rubber rings for increasing their isometric strength-endurance in the forearm muscles. The aim of this study was to ascertain whether such training influences oxygenation and endurance of forearm muscles at higher as well as lower testing intensities. Fourteen healthy young ice-climbers were divided and randomized into two groups.

Classification tree analysis of second neoplasms in survivors of childhood cancer.

Background: Reports on childhood cancer survivors estimated cumulative probability of developing secondary neoplasms vary from 3.3% to 25% at 25 years from diagnosis, and the risk of developing another cancer to several times greater than in the general population.

Methods: In our retrospective study, we have used the classification tree multivariate method on a group of 849 first cancer survivors, to identify childhood cancer patients with the greatest risk for development of secondary neoplasms.

Ewing sarcoma/PNET: 27 years of experience in Slovenia.

The study includes 91 patients treated for Ewing sarcoma between 1972 and 2002. Forty were younger and 51 were older than 16. The overall 5-year survival was 36%: 53.

The role of radiotherapy in the treatment of childhood intracranial germinoma: long-term survival and late effects.

Background: The aim of the present report was to evaluate the role of radiotherapy in the treatment of childhood intracranial germinoma in view of long-term survival and functional outcome.

Procedure: Nine children with histologically verified intracranial germinomas treated in Slovenia between 1983 and 1995 were reviewed. The four boys and five girls were 8.

Pediatric osteosarcoma: a 35-year experience in Slovenia.

The purpose of this study was to review all the children and adolescents treated for osteosarcoma in Slovenia between 1968 and 1997. Seventy-four patients were included in this retrospective study and classified according to the newly devised classification based on clinical and imaging studies. The overall survival rate is 48%.

Choroid plexus tumors: a review of 28-year experience.

The aims of the study were to review the patients with choroid plexus tumor (CPT) treated in Slovenia between 1972-1999, to calculate the incidence of CPTs, and to evaluate treatment results in respect to tumor histology and mode of therapy. Cancer Registry of Slovenia database was used for patientś identification. Histological specimens and medical records were reviewed.

Gonadal function in patients treated for leukemia in childhood.

Ovarian and testicular function were assessed in 67 long-term survivors (37 females, 30 males) treated for leukemia between 1973 and 1992. At diagnosis they were 1-16 (median 5) years old and had evaluation of gonadal function 4-25 (median 13) years later at the age of 13-31 (median 19). All had been treated with various combinations of chemotherapy (ChT) (including cyclophosphamide (CYC) and cytarabine in 32 patients), 62 patients had received prophylactic cranial irradiation with 12-49 (median 18) Gy, 2 patients had had craniospinal irradiation with 24 and 10 Gy respectively.

Second neoplasms after treatment of childhood cancer in Slovenia.

Background: The number of long time survivors of childhood cancer treatment is constantly increasing over the last decades as a result of advances in diagnosis and treatment. The occurrence of second neoplasms is one of most serious late effects observed in cancer survivors.

Methods: The risk of secondary neoplasm was studied in a cohort of 1,577 patients treated for childhood cancer registered in the Cancer Registry of Slovenia (CRS) between 1961 and 2000.

Medulloblastoma in children 0-3 years old: forty years' experience in slovenia.

Twenty-one children 0-3 years with MB were admitted 1960-1996, of 14 before treated 1984, 3 had no treatment, 5 had postoperative RT, one had radioactive gold IT. Seven treated 1986-1996 had preradiation Cht, 5 with HDCy. Of the 14 treated before 1984, 12 died within 1 year, one after 42 years in hypopharynx cancer, one is alive, of normal height and working.

Long-term sequelae in children treated for brain tumors: impairments, disability, and handicap.

Sixty-one long-term survivors, treated for brain tumors in childhood, were evaluated in term of neurological impairments, disability, and handicap. Thirty-eight patients (pts) (62%) had at least one impairment. Visual impairment was detected in 14 pts (24%), associated with recurrence (p = .

Topical topic: value of fine needle aspiration biopsy in childhood rhabdomyosarcoma: twenty-six years of experience in Slovenia.

Background: Chemotherapy (Cht) for rhabdomyosarcoma (RMS) given before local treatment can prevent mutilating surgery and high-dose irradiation (RT). Fine needle aspiration biopsy (FNAB) can confirm the diagnosis and neoadjuvant treatment can start without delay. The purpose of our study was to assess the role of FNAB in the management of childhood RMS in Slovenia.