Background: Electron therapy, vital for treating skin lesions and superficial tumors, demands precise electron cutouts to ensure accurate dose delivery. Traditional manual tracing methods introduce uncertainties and inefficiencies, necessitating innovative solutions for custom block creation.
Purpose: To introduce and validate the Optical Automatic Contour Tracing (O-ACT) method, enhancing electron cutout generation's accuracy and efficiency through optical imaging and software automation.
Background: Autism Spectrum Disorder (ASD) and Attention-Deficit/Hyperactivity Disorder (ADHD) are both associated with impairment in executive function, particularly in complex attention. Although previous studies using clinical assessments have attempted to delineate differences between these disorders, the findings have been inconclusive. Our study aims to elucidate the differences of endophenotype between ASD, ADHD, and their co-occurring condition utilizing a uniform computerized test.
View Article and Find Full Text PDFThis study used target, suspect, and non-target screening, to assess the presence of per- and polyfluoroalkyl substances (PFASs) in domestic (municipal) and industrial wastewater treatment plants (WWTPs) in South Korea. Target analysis quantified 20 PFASs in the WWTP effluents. Total concentration of PFASs ranged from 69.
View Article and Find Full Text PDFPhospholipid fatty acid (PLFA) analysis is used for characterizing microbial communities based on their lipid profiles. This method avoids biases from PCR or culture, allowing data collection in a natural state. However, PLFA is labor-intensive due to lipid fractionation.
View Article and Find Full Text PDFBackground And Purpose: The upgrade of major equipment can be disruptive to clinical operations and introduce risk as policy and procedures need to adapt to new technical possibilities and constraints. We describe here the transition from GammaMedPlus-iX to Bravos in a busy brachytherapy clinic, involving four afterloaders across two sites.
Material And Methods: Our clinic employs three high-dose-rate remote afterloaders in four dedicated treatment vaults at the main site and a fourth afterloader at a regional location.
Metalenses are instruments that manipulate waves and have exhibited remarkable capabilities to date. However, an important hurdle arises due to the severe hampering of the angular response originating from coma and field curvature aberrations, which result in a loss of focusing ability. Herein, we provide a blueprint by introducing the notion of a wide field-of-hearing (FOH) metalens, designed particularly for capturing and focusing sound with decreased aberrations.
View Article and Find Full Text PDFJ Appl Clin Med Phys
March 2024
Recently, CRISPR proteins have been recognized as promising candidates for drug development. However, there is still a lack of substances with the appropriate sensitivity and stability for targeted drug delivery systems. Zr is a radioactive isotope that emits positrons, allowing real-time in vivo tracking with proven safety.
View Article and Find Full Text PDFWidespread use of spray-type consumer products can raise significant concerns regarding their effects on indoor air quality and human health. In this study, we conducted non-target screening using gas chromatography-mass spectrometry (GC-MS) to analyze VOCs in 48 different spray-type consumer products. Using this approach, we tentatively identified a total of 254 VOCs from the spray-type products.
View Article and Find Full Text PDFMitochondrial DNA (mtDNA) leakage into the cytoplasm can occur when cells are exposed to noxious stimuli. Specific sensors recognize cytoplasmic mtDNA to promote cytokine production. Cytoplasmic mtDNA can also be secreted extracellularly, leading to sterile inflammation.
View Article and Find Full Text PDFThe greener chemical and enzymatic pretreatments for lignocellulosic biomasses are portraying a crucial role owing to their recalcitrant nature. Traditional pretreatments lead to partial degradation of lignin and hemicellulose moieties from the pretreated biomass. But it still restricts the enzyme accessibility for the digestibility towards the celluloses and the interaction of lignin-enzymes, nonproductively.
View Article and Find Full Text PDFThis study envisioned attaining the percipience of effective biohydrogen production from paper mill waste-activated sludge through low-temperature calcium peroxide-mediated bacterial pretreatment (TCP-BP). Floc dissociation with limited cell destruction was attained at a calcium peroxide dosage of 0.05 g/g suspended solids (SS) at 70 °C temperature.
View Article and Find Full Text PDFPurpose: The starting time for probiotic supplementation in preterm infants after birth varies widely. This study aimed to investigate the optimal time for initiating probiotics to reduce adverse outcomes in preterm or very low birth weight (VLBW) infants.
Methods: Medical records of preterm infants born at a gestational age (GA) of <32 weeks or VLBW infants in 2011-2020 were reviewed respectively.
In the dark fermentation of hydrogen, development of production host is crucial as bacteria act on substrates and produce hydrogen. The present study aimed to improve hydrogen production through the development of Clostridium acetobutylicum as a superior biohydrogen producer. Glyceraldehyde-3-phosphate dehydrogenase (GAPDH), which produces NADH/NADPH for metabolites and energy in primary pathways, was introduced to enhance hydrogen production.
View Article and Find Full Text PDFAccording to previous reports, most cases of inflammatory myopathy following messenger RNA (mRNA) vaccination can be classified as idiopathic inflammatory myopathy, particularly dermatomyositis, owing to their similar clinical features and courses. However, some patients have different clinical features and courses. We report a rare case of transient inflammatory myopathy involving the masseter muscle following the third dose of coronavirus disease 2019 (COVID-19) mRNA vaccination.
View Article and Find Full Text PDFMetalenses are attractive alternatives to conventional bulky refractive lenses owing to their superior light-modulating performance and sub-micrometre-scale thicknesses; however, limitations in existing fabrication techniques, including high cost, low throughput and small patterning area, have hindered their mass production. Here we demonstrate low-cost and high-throughput mass production of large-aperture visible metalenses using deep-ultraviolet argon fluoride immersion lithography and wafer-scale nanoimprint lithography. Once a 12″ master stamp is imprinted, hundreds of centimetre-scale metalenses can be fabricated using a thinly coated high-index film to enhance light confinement, resulting in a substantial increase in conversion efficiency.
View Article and Find Full Text PDFIdentification of novel, electricity-producing bacteria has garnered remarkable interest because of the various applications of electricigens in microbial fuel cell and bioelectrochemical systems. BBL25, an electricity-generating microorganism, uses various carbon sources and shows broader sugar utilization than the better-known MR-1. To determine the sugar-utilizing genes and electricity production and transfer system in BBL25, we performed an in-depth analysis using whole-genome sequencing.
View Article and Find Full Text PDFBackground: EBT4 was newly released for radiotherapy quality assurance to improve the signal-to-noise ratio in radiochromic film dosimetry. It is important to know its dose-response characteristics before its use in the clinic.
Purpose: This study aims to investigate and compare the dose-response curves of the Gafchromic EBT4 film for megavoltage and kilovoltage x-ray beams with different dose levels, scanning spatial resolutions, and sizes of region of interest (ROI).
Humidity-responsive structural coloration is actively investigated to realize real-time humidity sensors for applications in smart farming, food storage, and healthcare management. Here, humidity-tunable nano pixels are investigated with a 700 nm resolution that demonstrates full standard RGB (sRGB) gamut coverage with a millisecond-response time. The color pixels are designed as Fabry-Pérot (F-P) etalons which consist of an aluminum mirror substrate, humidity-responsive polyvinyl alcohol (PVA) spacer, and a top layer of disordered silver nanoparticles (NPs).
View Article and Find Full Text PDFCarotenoids are naturally occurring pigments that are widely distributed in algae, fungi, bacteria, and plants. Carotenoids play a significant role in the food, feed, cosmetic, nutraceutical, and pharmaceutical industries. These pigments are effectively considered as a health-promoting compounds, which are widely used in our daily diet to reduce the risk of chronic diseases such as cardiovascular diseases, cancer, acute lung injury, cataracts, neural disorders, etc.
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