Psychological mistreatment by married children in Korea: using the contextual theory to explain mistreatment of aging parents and parents-in-law.

Guided by the contextual theory of elder mistreatment, this study examined the psychological mistreatment (PM) of aging parents and parents-in-law by their married children and compared the risk factors of PM. We used nationally representative data on the adverse experiences of Korean adults in 2017 (n=2,974). Results showed similarities and differences in the PM of aging parents and parents-in-law.

Household food insecurity during childhood and subsequent health status: the early childhood longitudinal study--kindergarten cohort.

Objectives: We examined long-term patterns of household food insecurity in children from kindergarten through eighth grade and the association between those patterns and children's proxy-reported health status in eighth grade.

Methods: We obtained data from the Early Childhood Longitudinal Study-Kindergarten Cohort, a study that followed a nationally representative sample of students from kindergarten entry in 1998-1999 through eighth grade. We classified food insecurity according to the number of years of reported household food insecurity over 4 observation years.

Co-chaperone CHIP promotes aggregation of ataxin-1.

Recent studies demonstrated that co-chaperone/E3 ligase CHIP (C-terminus of hsp70-interacting protein) mediates the ubiquitylation and suppresses the aggregation of polyglutamine (polyQ) proteins, such as huntingtin or ataxin-3. In this study, we investigated the effects of CHIP on the degradation of another polyQ protein ataxin-1. Interestingly CHIP associates not only with the polyQ-expanded ataxin-1 but also with the normal ataxin-1.

The role of hydrogen peroxide produced by polychlorinated biphenyls in PMR1-deficient yeast cells.

Polychlorinated biphenyls (PCBs) are well-known recalcitrant environmental pollutants. Although the metabolism of the PCBs has been intensively studied, very little is known about their mechanism of toxicity in living organisms or how they are degraded. We have examined the effects of PCBs on two different yeast strains to determine their mechanism of action.