Extraction and Concentration of Waste Stems with Antioxidants and Anti-Melanogenesis Activity as a Novel Skin Whitening Agent for Natural Cosmetic Prototypes.

The root of (Willd.) is used commercially in different products, including dietary supplements, cosmetics, and teas, but its stem part is rarely used and studied. Therefore, this study evaluated the antioxidant and anti-melanogenesis activities of the bioactive fraction of stem and investigated whether the activated carbon decolorization technique would have an impact on its activity and chemical composition.

Anti-Wrinkle Effect of Leaf Extract: Evaluation of Antioxidant, Anti-Inflammation, and Clinical Activity.

leaf is an oriental herbal medicine that has been known for various pharmacological effects. However, its anti-wrinkle activity has not been fully evaluated. Therefore, we evaluated the anti-wrinkle effect of .

Evaluation of Anti-Melanogenesis Activity of Enriched Stem Extracts and Characterization of Its Phytochemical Components Using HPLC-PDA-ESI-MS/MS.

The root of (Willd.) is a widely used herbal medicine worldwide, whereas the stem of the plant is discarded or used as feed for livestock. To reuse and exploit the stem of as a resource, we investigated its potential as a skin-whitening agent.

Evaluation of the Antiwrinkle Activity of Enriched Isatidis Folium Extract and an HPLC-UV Method for the Quality Control of Its Cream Products.

Currently, many extracts from natural sources are added to cosmetic products for reducing facial aging and wrinkles. This study investigated the antiwrinkle activity of enriched extract of Isatidis Folium used for a novel antiwrinkle cream product. The result demonstrated that this enriched extract has excellent antiwrinkle activity by significantly inhibiting mRNA expression of matrix metalloproteinase-1, matrix metalloproteinase-3, and pro-inflammatory cytokines IL-1β and upregulating the mRNA expression of IL-4 and procollagen.

The Effects of Non-Thermal Atmospheric Pressure Plasma treated Titanium Surface on Behaviors of Oral Soft Tissue Cells.

Here, we investigated the possible use of the technology known as non-thermal atmospheric pressure plasma on integration and control of cytokine release of soft tissue on titanium surface. After NTAPP was applied to titanium samples, changes of surface characteristics were measured as topographical features, contact angle, surface tension, and with X-ray photoelectron spectroscopy (XPS). Protein absorption was evaluated using a bovine serum albumin absorption assay.

Effect of the ultraviolet light treatment and storage methods on the biological activity of a titanium implant surface.

Objective: We evaluated whether the biological activity of the surface of titanium, when stored in an aqueous solution, in low vacuum, and under ambient conditions after ultraviolet light (UV) treatment is comparable to that of the surface immediately after UV treatment for 15min and that after dielectric barrier discharge (DBD) plasma treatment for 15min.

Methods: Grade IV titanium discs with machined surfaces were irradiated with UV and their surface properties were evaluated immediately and after storage for 28days in distilled HO (dHO), a vacuum desiccator (31.325kPa), and a sealed container under air.

Bacterial attachment on titanium surfaces is dependent on topography and chemical changes induced by nonthermal atmospheric pressure plasma.

Here, we investigated the antibacterial effects of chemical changes induced by nonthermal atmospheric pressure plasma (NTAPP) on smooth and rough Ti. The morphologies of smooth and rough surfaces of Ti were examined using scanning electron microscopy (SEM). Both Ti specimens were then treated for 10 min by NTAPP with nitrogen gas.

Overcoming the biological aging of titanium using a wet storage method after ultraviolet treatment.

We evaluated whether the biological activity of the surface of titanium, when stored in an aqueous solution after ultraviolet (UV) treatment, is comparable to that of the surface immediately after UV treatment. We subjected Grade IV titanium discs with machined surfaces to UV radiation for 15 min and then tested them immediately and after storage for 28 days, with and without distilled HO (dHO). We evaluated the surface characteristics using surface profiling, contact angle analysis, X-ray photoelectron spectroscopy, and in terms of the surface zeta-potential.

Non-thermal atmospheric pressure plasma functionalized dental implant for enhancement of bacterial resistance and osseointegration.

Objective: Even though roughened titanium (Ti) and Ti alloys have been clinically used as dental implant, they encourage bacterial adhesion, leading to failure of the initial stability. Here, the non-thermal atmospheric pressure plasma jet (NTAPPJ) functionalized Ti and Ti alloy were investigated to promote cellular activities but inhibit the initial attachment of the adherent pioneer bacterium, Streptococcus sanguinis, without topographical changes.

Methods: After the produced radicals from NTAPPJ were characterized, bacterial adhesion to specimens was assessed by PrestoBlue assay and live-dead staining with or without the NTAPPJ functionalizing.

Time-dependent effects of ultraviolet and nonthermal atmospheric pressure plasma on the biological activity of titanium.

Here, we evaluated time-dependent changes in the effects of ultraviolet (UV) and nonthermal atmospheric pressure plasma (NTAPPJ) on the biological activity of titanium compared with that of untreated titanium. Grade IV machined surface titanium discs (12-mm diameter) were used immediately and stored up to 28 days after 15-min UV or 10-min NTAPPJ treatment. Changes of surface characteristics over time were evaluated using scanning electron microscopy, surface profiling, contact angle analysis, X-ray photoelectron spectroscopy, and surface zeta-potential.

Long-Term Antibacterial Performance and Bioactivity of Plasma-Engineered Ag-NPs/TiO₂.

We prepared TiO2 nanotubes (NT) on commercially pure titanium (cp-Ti) substrate by plasma electrolyte oxidation and adapted magnetron sputtering for incorporation of Ag-nanoparticles (Ag-NPs) onto the nanotubes (Ag-NPs/TiO2 nanotube). Power input to the Ag target per unit time was varied (5, 10, 15 W/cm2) to fabricate different shapes of Agnanoparticles onto the nanotubes while net energy input was fixed by maintaining a constant total sputter time (30, 15, 10 s, respectively). For investigation of experimental samples' characteristics, FE-SEM, TEM, EDS, XRD, XPS, SPM analysis and contact angles measurement was carried out.

Endoscopically observed lower esophageal capillary patterns.

Background: It has been reported that there are four zones of distinct venous patterns around the gastroesophageal junction (GEJ); i.e. truncal, perforating, palisade (PZ) and gastric zones.

[Clinical outcome in cases of viral breakthrough during lamivudine therapy in chronic hepatitis B patients].

Background/aims: Long-term lamivudine therapy can induce the emergence of lamivudine resistant hepatitis B virus (HBV) mutants. Clinically emergence of the mutant is expressed by the reappearance of disappeared HBV DNA in serum. Continued lamivudine treatment has been usually recommended in cases of viral breakthrough.