Publications by authors named "Jeong Sim Kim"
Article Synopsis
- Korea experienced a nationwide outbreak of hepatitis A from 2006 to 2008, focusing on genotypes IA and IIIA among 595 symptomatic patients.
- Out of 556 participants, genotypic analysis showed that both IA and IIIA genotypes were equally prevalent, but there was a shift from predominantly IA to IIIA over the study period.
- Patients with genotype IIIA exhibited more severe symptoms and higher liver enzyme levels compared to those infected with genotype IA, indicating potentially worse clinical outcomes for IIIA infections.
The clinical outcome of symptomatic hepatitis A and the incidence and clinical characteristics of atypical presentation of hepatitis A were studied using prospective, multicenter design. The atypical presentation included delayed anti-hepatitis A virus (HAV) immunoglobulin M (IgM) seroconversion defined as positive anti-HAV IgM on the repeated test within 7 days of hospital admission after the initially negative result, prolonged cholestasis, and acute kidney injury (AKI). A total of 595 patients with symptomatic hepatitis A requiring hospital admission were enrolled prospectively from September 2006 to August 2008 in four major hospitals in a Korean city with a population of approximately 1 million.
View Article and Find Full Text PDFHepatitis E virus (HEV) was originally identified as the etiological agent of non-HAV enterically transmitted hepatitis. One HEV strain (FJ763142) was identified from an acute viral hepatitis E patient with IgM anti-HEV in Korea. The complete genome sequence consisted of 7,238 nucleotides (nt) plus a 22-nt poly(A) tail.
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