Publications by authors named "Jeong S Kim"

Background: The primary treatment for cervical insufficiency is cervical cerclage (mechanical support) with vaginal progesterone (biochemical support). Cerclage is a surgical procedure that mechanically increases the tensile capacity of the cervix. Therefore, it is necessary to analyse the effects of cerclage from a mechanical point of view.

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  • Endometrial cancer is a serious gynecological issue, and the study focused on the role of TBK1, a kinase involved in inflammation and immunity, in this cancer type.
  • Research found that low TBK1 expression is linked to better patient outcomes, and inhibiting TBK1 with amlexanox reduced cancer cell growth and migration.
  • The effects of amlexanox were shown to work through the AKT/NF-κB signaling pathway, suggesting a new direction for cancer treatments targeting TBK1 in endometrial cancer.
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Language learning through computer games has been suggested to enhance language abilities compared with traditional learning methods. Training in language skills may also improve self-control and reduce problematic behaviors in children and adolescents. We hypothesized that computer game-based language training could be more effective than classical language instruction.

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Red beetroots, rich in betanin, may act as prebiotics and impact gut microbiota. Because the human gut microbiota is unique to each person, the effectiveness of prebiotics varies with the enterotype. In this study, we hypothesized that the effects of red beetroot powder (RP) and betanin pigment (BP) would differ depending on the enterotype.

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This study was conducted to identify the key elements of transitional care for families with pre-term infants in South Korea. We used an integrative review methodology proposed by Whittemore and Knafle. During the problem identification step, the review question was constructed via the population, intervention, outcome, and timeframe (PIOT) format.

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COVID-19 pandemic was accompanied by many healthcare-related issues. Concrete national data regarding the care performance of critical ill cases of COVID-19 does not exist in Korea. The current study aimed to describe the treatment outcome and healthcare resource utilization of critically ill COVID-19 patients.

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Currently, the treatment of hepatocellular carcinoma (HCC) is yet to be determined, alternatively, flavonoids or alkaloids from nature have been considered as significant mediators against HCC. In the scenario, we pioneered the most significant agent(s) in either flavonoid(s) or alkaloid(s) against HCC with cheminformatics, bioinformatics, computer screening tools and quantum chemistry concept. In prospect, the intent was to provide the theoretical scaffold in the myriad natural organic molecules.

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We consider multipartite quantum state discrimination and provide a specific relation between the properties of entanglement witness and quantum nonlocality inherent in the confidence of measurement. We first provide the definition of the confidence of measurement as well as its useful properties for various types of multipartite measurement. We show that globally-maximum confidence that cannot be achieved by local operations and classical communication strongly depends on the existence of a certain type of entanglement witness.

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  • Female urethral diverticulum (UD) is a rare condition during pregnancy with no clear management guidelines, typically approached conservatively.
  • A case report details a 39-year-old pregnant woman who developed a UD diagnosed via ultrasound and MRI, leading to a cesarean section due to preterm labor, with the condition persisting post-delivery.
  • The study concludes that UD can occur during pregnancy, with MRI being effective for diagnosis, and recommends surgical intervention if UD remains after childbirth.
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  • - The study investigates how Drynaria rhizome (DR) and gut microbiota (GM) work together to reduce obesity (OB), highlighting their mutual benefits in improving health.
  • - Researchers utilized DGSTM networks, Molecular Docking Test (MDT), and Density Functional Theory (DFT) to identify crucial molecular interactions between DR and GM that contribute to weight loss.
  • - Key stable compounds were identified, including NR1H3 and PPARG from DR, along with various ligands from GM, suggesting that DR-GM may effectively target the PPAR signaling pathway to combat obesity.
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  • The study investigates the significance of tumor size in T3b differentiated thyroid cancer (DTC) by analyzing data from 6,282 patients who had thyroid surgery between 2000 and 2017.
  • T3b tumors were categorized into three groups based on size—T3b-1 (≤2 cm), T3b-2 (2-4 cm), and T3b-3 (>4 cm)—to evaluate their impact on survival outcomes.
  • Findings suggest that T3b-1 tumors show survival rates similar to T1 tumors, indicating a potential need to reclassify T3b-1 as T1 for better prognostic accuracy in cancer staging.
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Purpose: As introduced, multimodal pain management bundle for ileostomy reversal may be considered to reduce postoperative pain and hospital stay. The aim of this study was to evaluate clinical efficacy of perioperative multimodal pain bundle for ileostomy.

Methods: Medical records of patients who underwent ileostomy reversal after rectal cancer surgery from April 2017 to March 2020 were analyzed.

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Type 2 diabetes mellitus (T2DM), nonalcoholic fatty liver disease (NAFLD), obesity (OB) and hypertension (HT) are categorized as metabolic disorders (MDs), which develop independently without distinct borders. Herein, we examined the gut microbiota (GM) and (SC) to confirm their therapeutic effects via integrated pharmacology. The overlapping targets from the four diseases were determined to be key protein coding genes.

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The incidence of concomitant thyroid cancer in Graves' disease varies and Graves' disease can make the diagnosis and management of thyroid nodules more challenging. Since the majority of Graves' disease patients primarily received non-surgical treatment, identifying biomarkers for concomitant thyroid cancer in patients with Graves' disease may facilitate planning the surgery. The aim of this study is to identify the biomarkers for concurrent thyroid cancer in Graves' disease patients and evaluate the impact of being overweight on cancer risk.

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  • The study evaluated the effectiveness and tolerability of combining irbesartan (IRB) and amlodipine (AML) in treating essential hypertension when IRB alone was insufficient.
  • Two phase III clinical trials in Korea involved 428 patients and compared combinations of IRB/AML to placebo over 8 weeks, focusing on changes in mean sitting systolic blood pressure (MSSBP).
  • Results showed significant reductions in MSSBP in the combination groups compared to monotherapy, with adverse events occurring in a small percentage of participants, indicating the combined therapy was both effective and tolerable.
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  • The study compared renovated double J stents (DJS) with conventional stents using ureter models to assess their effectiveness for different ureteral diseases.
  • Two ureter models were tested: one with stenosis and one without, using various sizes and designs of DJS to evaluate urine flow.
  • Results showed that renovated stents had better flow rates in models without stenosis but did not perform significantly better than conventional stents in models with stenosis.
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Background: Cilostazol has a vasodilatory function that may be beneficial for patients with vasospastic angina (VSA). We conducted a randomized, open-label, controlled trial to compare the efficacy and safety of long-acting cilostazol and isosorbide mononitrate (ISMN) for VSA.

Methods: The study included patients with confirmed VSA between September 2019 and May 2021.

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Backgruound: There is debate about ultrasonography screening for thyroid cancer and its cost-effectiveness. This study aimed to evaluate the cost-effectiveness of early screening (ES) versus symptomatic detection (SD) for differentiated thyroid cancer (DTC) in Korea.

Methods: A Markov decision analysis model was constructed to compare the cost-effectiveness of ES and SD.

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  • Metastasis to cervical lymph nodes is common in differentiated thyroid cancer, and this study explored the effectiveness of measuring washout CYFRA 21-1 levels alongside thyroglobulin (Tg) for diagnosing such metastases.
  • The study included 53 patients undergoing thyroid surgery, where specific lymph nodes were sampled and the levels of Tg and CYFRA 21-1 were compared between metastatic and benign nodes.
  • Combined analysis of washout Tg and CYFRA 21-1 led to a diagnostic accuracy of 92.5%, outperforming each marker individually, and providing valuable information when cytology results are inconclusive.
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Purpose: Recurrent laryngeal nerve injury after thyroid surgery may cause vocal cord palsy (VCP), which leads to unexpected additional costs. In recent years, intraoperative neural monitoring (IONM) has been used to lower the incidence rate of VCP. This study aimed to analyze postoperative management costs for patients with papillary thyroid carcinoma (PTC).

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