Publications by authors named "Jeong Ryul Choi"
Article Synopsis
- Researchers have developed a new type of polymer micelles called copper(II) arsenite-integrated polymer micelles (CuAS-PMs) that can generate reactive oxygen species (ROS) to target cancer cells.
- These micelles are made using a unique method that allows them to be stable in serum while releasing toxic components under specific conditions in cancer cells.
- Animal studies show that CuAS-PMs effectively reduce tumor growth without causing harmful side effects, suggesting they could lead to new treatments that increase oxidative stress in cancerous tissues.
Mussel-inspired poly(L-DOPA)-templated mineralization for calcium phosphate-assembled intracellular nanocarriers.
Colloids Surf B Biointerfaces
September 2017
We developed a calcium phosphate (CaP)-assembled polymer nanocarrier for intracellular doxorubicin (DOX) delivery based on a mussel-inspired mineralization approach. A DOX-loaded core-shell polymer nanoparticle (DOX-NP) consisting of a poly(3,4-dihydroxy-l-phenylalanine) (PDOPA) core and a poly (ethylene glycol) (PEG) shell was utilized as a nanotemplate for CaP mineralization. The mean hydrodynamic diameter of the DOX-loaded CaP-mineralized polymer nanoparticles (DOX-CaP-NPs) was 154.
View Article and Find Full Text PDF