Publications by authors named "Jens Tobias Hartung"
Antiresorptive therapy in combination with radiation results in enhanced risk for necrosis and associated complicatifions.
Katharina Theresa Obermeier Wenko Smolka Benjamin Palla Moritz Kraus David Steybe Jens Tobias Hartung
Oral Surg Oral Med Oral Pathol Oral Radiol
January 2025
Article Synopsis
- Patients treated with both antiresorptive medication and radiotherapy in the head and neck are at increased risk for developing complications such as jaw necrosis, fractures, and recurrence of conditions.
- The study involved 17 patients who were compared to larger control groups, revealing significant differences in outcomes, with those receiving combined treatment facing higher risks.
- The findings suggest that the combination of these treatments leads to a four-fold increase in recurrence risk and a higher likelihood of serious complications compared to patients receiving just one type of treatment.
A total of 7% of all benign bone lesions are diagnosed as fibrous dysplasia (FD). The symptoms of FD of the jaw range from asymptomatic to dental anomalies, pain and facial asymmetry. Due to its resemblance to other fibro-osseous bone lesions, misdiagnosis often occurs and can lead to inadequate treatment.
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