Impact of increased hematocrit on right ventricular afterload in response to chronic hypoxia.

Chronic hypoxia causes chronic mountain sickness through hypoxia-induced pulmonary hypertension (HPH) and increased hematocrit. Here, we investigated the impact of increased hematocrit and HPH on right ventricular (RV) afterload via pulmonary vascular impedance. Mice were exposed to chronic normobaric hypoxia (10% oxygen) for 10 (10H) or 21 days (21H).

Evaluation of the response to vaccination with hepatitis B vaccine in pediatric patients diagnosed with celiac disease.

Background: A gap exists in the literature on celiac disease populations and the response to hepatitis B vaccination.

Objective: To identify pediatric patients with celiac disease who received the primary hepatitis B vaccination and investigate their response to vaccine.

Design/methods: Patients underwent blood draw for hepatitis B surface antibody titers.