Publications by authors named "Jenny Ruedlinger"

Article Synopsis
  • Processed meat consumption is rising in Latin America, but there is limited research on its health impacts compared to developed countries, where it's linked to diseases like cancer and heart issues.
  • A study in a Chilean agricultural county (MAUCO) analyzed dietary data from 7,841 participants, finding that 8% consumed processed meat frequently (≥5 times/week).
  • Factors like being male, younger, employed, and having high intakes of red meat, dairy, and sugary snacks/drinks were associated with higher processed meat consumption, which correlated with chronic diseases, especially cardiovascular problems.
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In-stent restenosis (ISR) is one of the main complications in patients undergoing percutaneous coronary angioplasty, and microRNAs participate in the contractile-to-synthetic phenotypic switch of vascular smooth muscle cells, a hallmark of restenosis development. MicroRNAs (miRNAs) can be released into circulation from injured tissues, enticing a potential role as noninvasive biomarkers. We aimed to evaluate circulating levels of miRNA-23b, miRNA-143, and miRNA-145 as diagnostic markers of ISR.

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Epstein-Barr virus (EBV) is an etiological agent for gastric cancer with significant worldwide variations. Molecular characterizations of EBV have shown phylogeographical variations among healthy populations and in EBV-associated diseases, particularly the cosegregated BamHI-I fragment and XhoI restriction site of exon 1 of the gene. In the Americas, both cosegregated variants are present in EBV carriers, which aligns with the history of Asian and European human migration to this continent.

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Clopidogrel is an antiplatelet drug especially used in patients undergoing percutaneous coronary interventions (PCI). Polymorphisms within can result in important interindividual variations regarding therapeutic efficacy. Therefore, we aimed to evaluate the impact of the CYP2C192 variant (rs4244285) on in-stent restenosis occurrence in Chilean patients who underwent PCI and received clopidogrel.

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Article Synopsis
  • Low adiponectin levels are linked to obesity, diabetes, coronary disease, and genetic factors in a Chilean adult population.
  • The study examined 108 individuals, focusing on physical activity, cardiovascular risk, and specific genetic polymorphisms related to adiponectin levels.
  • Findings revealed that lower adiponectin levels were significantly associated with factors such as waist circumference, gender, obesity, physical inactivity, and insulin resistance, while genetic variations had minimal impact.
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Background: Ruta graveolens L. (R. graveolens) is a medicinal plant employed in non-traditional medicines that has various therapeutic properties, including anthelmintic, and vasodilatory actions, among others.

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