Publications by authors named "Jenny McCloskey"
Article Synopsis
- Australia implemented a national HPV vaccination program for girls in 2007 and boys in 2013, achieving strong coverage among both groups, with a study focusing on HPV prevalence among men aged 18-35 based on their vaccination status.
- Of the 1,625 men studied, the HPV prevalence was similar for vaccinated and unvaccinated men who have sex with women (10.6% vs. 10.7%), while unvaccinated men who have sex with men had a significantly higher prevalence (40.3%) compared to vaccinated men (29.9%).
- The findings highlight that universal vaccination is crucial for all adolescents, particularly to ensure that men who have sex with men also gain protection from HPV, as older
Article Synopsis
- The study aimed to investigate changes in syphilis positivity rates among women and heterosexual men in major Australian cities from 2011 to 2019, focusing on various health determinants.
- A total of 88,562 first tests were analyzed, revealing that the syphilis positivity rate increased for both groups over the years, with 0.34% of women and 0.66% of men testing positive.
- Socio-economic disadvantage, Indigenous status, and recent injection drug use significantly contributed to higher positivity rates, while bisexual women and those engaged in recent sex work showed lower rates compared to heterosexual women.
Background And Aim: Human papilloma virus-associated anal intraepithelial neoplasia (AIN) precedes most anal cancers and can be detected at colonoscopy. We aimed to quantify AIN detection rates in a general population undergoing colonoscopy.
Methods: A retrospective review of a community-based practice for 2 years until December 2019 was conducted.
Background: Anal intraepithelial neoplasia is associated with high-risk human papillomavirus (hrHPV) as a precursor to anal cancer. However, factors other than hrHPV are likely to be involved and further study of cofactors is required because of the possibility of syndemic interactions.
Methods: Three hundred and fourteen patients underwent 457 operations.
Background: Human papillomavirus (HPV)-related anal cancer lesions are often found adjacent to the squamocolumnar junction (SCJ). We have assessed the histopathology and associated HPV genotypes in anal SCJ lesions in surgically excised anal warts in HIV-negative and -positive patients.
Methods: Histopathology identified 47 squamous intraepithelial lesions (SILs) adjacent to the SCJ amongst a total of 145 cases of clinically diagnosed anal condylomata.
Genetic variation of 49 human papillomavirus (HPV) 6 and 22 HPV11 isolates from recurrent respiratory papillomatosis (RRP) (n = 17), genital warts (n = 43), anal cancer (n = 6) and cervical neoplasia cells (n = 5), was determined by sequencing the long control region (LCR) and the E6 and E7 genes. Comparative analysis of genetic variability was examined to determine whether different disease states resulting from HPV6 or HPV11 infection cluster into distinct variant groups. Sequence variation analysis of HPV6 revealed that isolates cluster into variants within previously described HPV6 lineages, with the majority (65%) clustering to HPV6 sublineage B1 across the three genomic regions examined.
View Article and Find Full Text PDFBackground: The level of agreement between anal cytology and histopathology is not clear with only a few studies evaluating the reliability of anal specimen reporting. Australian data in relation to this are limited.
Methods: The results of paired anal cytology and histopathology specimens received between 2002 and 2008 from patients who were referred within the sexual health clinic were retrieved from the anatomical pathology database.
Background: External genital warts are a common sexually transmitted viral disease. We describe the patterns of treatment for initial presentations of external genital warts (EGWs) in Australian sexual health centers.
Methods: This was a retrospective audit of 489 case notes from consecutive individuals who presented with a new diagnosis of EGWs to 1 of 5 major sexual health clinics in Australia.
Background: Partner notification is essential to interrupt transmission of sexually transmissible infections. We surveyed the attitudes to partner notification of general practitioners seeing 1-5 cases of chlamydia annually.
Methods: We collected data on chlamydia notifications received in Western Australia from 1 July 2007 to 30 June 2008.