Publications by Jenny K Furth

Publications by authors named "Jenny K Furth"

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Male and female germline specific expression of an EGFP reporter gene in a unique strain of transgenic rats.

Jennifer T Cronkhite Carola Norlander Jenny K Furth Göran Levan David L Garbers

Dev Biol

August 2005

A rat line was generated in which genomic integration of a ROSA-EGFP transgene resulted in exclusive expression of EGFP in the germ cells of both sexes. EGFP expression was uniform and robust in cleavage stage embryos beginning at the late 2-cell stage and continuing through blastocyst development where expression became restricted to cells of the inner cell mass. Subsequent analysis showed high EGFP expression exclusively in primordial, embryonic, and adult germ cells.

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- Jenny K Furth's research primarily focuses on the development and analysis of transgenic organisms, particularly in understanding germline expression patterns through the use of reporter genes.
- One of her notable findings includes the creation of a unique strain of transgenic rats where the EGFP reporter gene is expressed specifically and robustly in the germ cells of both male and female rats, beginning from early embryonic stages.
- The study highlights the reliable expression of EGFP from the late 2-cell stage up to the blastocyst stage, with expression eventually confined to primordial and adult germ cells, providing insights into germline biology and potential applications in genetic studies.

Publications by authors named "Jenny K Furth"

Male and female germline specific expression of an EGFP reporter gene in a unique strain of transgenic rats.

Synopsis of recent research by authors named "Jenny K Furth"