Mannose-binding lectin deficiency and predisposition to recurrent infection in adults.

Aims: The effects of mannose-binding lectin (MBL) deficiency are well known in children and in those with a compromised immune system. However, its effects in adults are debateable, with little research having been carried out in the UK regarding infection risk in otherwise healthy adults with an MBL deficiency.

Methods: Using an ELISA, we investigated the prevalence of MBL deficiency in both healthy adults and those with recurrent infection.