Publications by authors named "Jenny Gh Low"
Article Synopsis
- The study focuses on assessing T cell responses to SARS-CoV-2 through a new, simple test that measures cytokines after stimulating whole blood with spike protein peptides.
- The test was evaluated in various groups, including vaccinated individuals and COVID-19 patients, and showed sensitivity comparable to traditional methods.
- Results indicated that T cell responses were similar in vaccinated and convalescent individuals, but varied widely among individuals, highlighting the need to measure both antibody and T cell immunity for better understanding vaccine effectiveness.
Dengue virus (DENV), a mosquito-borne pathogen, causes systemic infections. There are no clear guidelines regarding the screening of donor blood is used in endemic countries to prevent blood transfusion or transplant-associated dengue. DENV has been shown to be detected in urine samples even when DENV viremia is undetectable.
View Article and Find Full Text PDFIntroduction: Respiratory virus (RV) infections have been implicated in acute exacerbation cardiopulmunary conditions. This study aimed to determine the prevalence of RV infections in patients admitted to the cardiology unit with acute decompensated heart failure (ADHF) in a tertiary hospitals in Singapore.
Materials And Methods: This was a single-centre, prospective observational study.
Development of antiviral therapy against acute viral diseases, such as dengue virus (DENV), suffers from the narrow window of viral load detection in serum during onset and clearance of infection and fever. We explored a biomarker approach using 18F-fluorodeoxyglucose (18F-FDG) PET in established mouse models for primary and antibody-dependent enhancement infection with DENV. 18F-FDG uptake was most prominent in the intestines and correlated with increased virus load and proinflammatory cytokines.
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