Publications by authors named "Jenny Gallagher"
Article Synopsis
- The study investigates the effect of low-magnitude mechanical signals (LMMS) on preserving bone mineral density (BMD) in malnourished adolescents and young adults with anorexia nervosa over a 6-month period.
- A total of 837 female adolescents were screened, with 317 qualifying for the trial, and 40 participants completed it, using a placebo-controlled approach for the intervention.
- Results showed no significant changes in total volumetric BMD between the LMMS and placebo groups, though some positive changes were observed in cross-sectional area at the tibia site in the LMMS group.
Background: The global COVID-19 pandemic disproportionately affected certain populations and its management differed between countries. This national study describes characteristics and outcomes of COVID-19 in patients with cancer in Australia.
Methods: We performed a multicentre cohort study of patients with cancer and COVID-19 from March 2020 to April 2022.
Community children's nurses provide a vital service between the hospital and home environment, supporting children, young people and families with their health needs. In the UK, the number of educational pathways providing a specialist practitioner qualification in community children's nursing has declined significantly in recent years. This has left many community children's nursing services with little or no access to educational programmes, despite the rising demand.
View Article and Find Full Text PDFObjective: To estimate the efficacy and safety of a novel nonhormonal therapeutic agent, cabergoline, compared with that of the standard clinical therapy, norethindrone acetate (NETA), for the treatment of endometriosis-associated pain in young women with endometriosis.
Design: Randomized, double-blind, placebo-controlled pilot study.
Setting: Tertiary care center.
Reactive oxygen species (ROS) generated during exercise are considered integral for the health-promoting effects of exercise. However, the precise mechanisms by which exercise and ROS promote metabolic health remain unclear. Here, we demonstrate that skeletal muscle NADPH oxidase 4 (NOX4), which is induced after exercise, facilitates ROS-mediated adaptive responses that promote muscle function, maintain redox balance, and prevent the development of insulin resistance.
View Article and Find Full Text PDFStudy Objectives: Hypothalamic amenorrhea is common in adolescents and young adults (AYAs) with anorexia nervosa (AN), and ovarian reserve is not routinely assessed. AN increases rates of fertility problems, but how or when AN negatively influences future fertility is unclear. We sought to determine whether biomarkers of ovarian reserve were impacted in AYA with AN.
View Article and Find Full Text PDFPurpose: While endometriosis is recognized to have a high patient burden for adults, the level of morbidity it causes for adolescents has been understudied, and may be minimized by clinicians. The purpose of this study was to determine whether endometriosis has a significant impact on quality of life (QOL) for adolescents and young adults.
Methods: Five hundred and sixty-seven participants (360 cases and 207 controls) aged <25 years old who are enrolled in the Women's Health Study: From Adolescence to Adulthood longitudinal study were included in this analysis.
Study Objective: To explore the potential occurrence of long-term side effects and tolerability of gonadotropin-releasing hormone agonist (GnRHa) plus 2 different add-back regimens in adolescent patients with endometriosis.
Design: Follow-up questionnaire sent in 2016 to patients who participated in a drug trial between 2008 and 2012.
Setting: Tertiary care center in Boston, Massachusetts.