Publications by authors named "Jenny Beaud"

Article Synopsis
  • Aging leads to changes in bone marrow (BM) and blood plasma cytokine levels, indicating a process called inflammaging.
  • In a study with 94 healthy volunteers, researchers found that certain cytokines increased or decreased with age, highlighting the complex relationship between aging and immune response.
  • The findings may help in understanding conditions linked to aging, such as myeloid malignancies and inflammatory diseases, by providing reference values for blood and bone marrow cytokine levels.
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Clonal hematopoiesis (CH) of indeterminate potential has been described in blood samples from large series of patients. Its prevalence and consequences are still not well understood because sequencing methods vary and because most studies were performed in cohorts comprising individuals with nonhematologic diseases. Here, we investigated the frequency of CH in 82 paired bone marrow and blood samples from carefully selected healthy adult volunteers.

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Occurrence of two different hematological malignancies is very infrequent, and it is nevertheless important not to neglect basic examinations in patients follow-up. A 65-year-old patient was referred to our institution for his chronic lymphocytic leukemia (CLL) checkup; we report the different steps leading to the diagnosis of a second hematological malignancy.

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