Objective: To develop an evidence-based practice project to evaluate the effect of delaying a newborn's first bath on exclusive breastfeeding rates at discharge.
Design: A pre- and post-implementation evaluation of the effect of delaying the first bath on exclusive breastfeeding rates at discharge.
Setting: A postpartum unit in a southern California community hospital.
Background: The Trauma Quality Improvement Project (TQIP) uses an injury prediction model for performance benchmarking. We hypothesize that at a Level I high-volume penetrating trauma center, performance outcomes will be biased due to inclusion of patients with nonsurvivable injuries.
Methods: Retrospective chart review was conducted for all patients included in the institutional TQIP analysis from 2013 to 2014 with length of stay (LOS) less than 1 day to determine survivability of the injuries.
Fatty acid binding protein 6 (FABP6) is a potential drug discovery target, which, if inhibited, may have a therapeutic benefit for the treatment of diabetes. Currently, there are no published inhibitors of FABP6, and with the target believed to be amenable to fragment-based drug discovery, a structurally enabled program was initiated. This program successfully identified fragment hits using the surface plasmon resonance (SPR) platform.
View Article and Find Full Text PDFThe Trauma Quality Improvement Program (TQIP) reports a feasible mortality prediction model. We hypothesize that our institutional characteristics differ from TQIP aggregate data, questioning its applicability. We conducted a 2-year (2008 to 2009) retrospective analysis of all trauma activations at a Level 1 trauma center.
View Article and Find Full Text PDFPurpose: : This study was conducted to evaluate the effects of education on knowledge and interrater reliability of neurovascular assessments with 2-point discrimination (2-PD) test among pediatric orthopaedic nurses.
Methods: : A pre- and posttest study was done among 60 nurses attending 2-hour educational sessions. Neurovascular assessments with 2-PD test were performed on 64 casted pediatric patients by the nurses and 5 nurse experts before and after the educational sessions.
Aims: The ability of mesenchymal stem cells (MSCs) to heal the chronically injured heart remains controversial. Here we tested the hypothesis that autologous MSCs can be safely injected into a chronic myocardial infarct scar, reduce its size, and improve ventricular function.
Methods And Results: Female adult Göttingen swine (n = 15) underwent left anterior descending coronary artery balloon occlusion to create reproducible ischaemia-reperfusion infarctions.