Publications by authors named "Jennifer Sumner"
Objective: Neighborhood characteristics can influence cardiometabolic health, including during the perinatal period. However, maternal health research has largely examined the influence of objective neighborhood measures, limiting insights into psychological and social processes. We examined associations of perceived neighborhood disorder and social cohesion with maternal cardiometabolic risk 1 year postpartum and explored potential pathways of psychological distress and physical activity.
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- Despite progress in recognizing and diagnosing spontaneous coronary artery dissection (SCAD) in the last decade, there is still limited understanding of its mechanisms, contributing factors, and effective treatments.
- The text highlights research gaps in SCAD and suggests strategies like patient advocacy, independent registries, and specialized centers to improve clinical care and research outcomes.
- Additionally, it presents a patient-centered clinical care and research framework developed by the SCAD Alliance and International SCAD registry as a model to enhance understanding and management of this condition.
Given their sudden onset and life-threatening consequences, strokes and transient ischemic attacks (TIAs) can trigger posttraumatic stress disorder (PTSD). To gain a deeper understanding of the potential influence of factors in patients' descriptions of these medical events on PTSD, we conducted a standardized trauma interview with a convenience sample of patients hospitalized for suspected stroke/TIA (N = 98) to assess the details and emotional experience of the stroke/TIA event. Three researchers reviewed the interviews and the research literature on risk and protective factors for PTSD.
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- - The study aimed to explore the co-design of remote patient monitoring (RPM) technology for hospitalized patients, assessing its effectiveness, the co-design methods used, and the barriers and facilitators encountered in this process
- - A systematic review analyzed 3334 reports, ultimately highlighting 17 relevant projects focusing on various monitoring scenarios (like surgical, intensive care, and rehabilitation), but none assessed the efficacy of their RPM technologies
- - Most projects employed co-design methods such as needs assessment and prototyping, while pilot studies evaluated aspects like usability and satisfaction instead of direct clinical outcomes.
Objective: Posttraumatic stress disorder (PTSD) has been linked with menopause symptoms (eg, vasomotor, urinary) and their sequelae (eg, sexual difficulties). However, PTSD is a heterogeneous disorder, and less is known about which aspects may be most associated with menopause-related health.
Methods: Using confirmatory factor analyses, we evaluated five structural models of PTSD symptoms in 208 predominately postmenopausal women veterans (aged 45-64 years).
Due to rapid technological advancements, remote patient monitoring (RPM) technology has gained traction in recent years. While the effects of specific RPM interventions are known, few published reviews examine RPM in the context of care transitions from an inpatient hospital setting to a home environment. In this systematic review, we addressed this gap by examining the impacts of RPM interventions on patient safety, adherence, clinical and quality of life outcomes and cost-related outcomes during care transition from inpatient care to a home setting.
View Article and Find Full Text PDFBackground: Post-traumatic stress disorder (PTSD) is associated with increased rates of incident ischemic heart disease (IHD) in women.
Objectives: The purpose of this study was to determine mechanisms of the PTSD-IHD association in women.
Methods: In this retrospective longitudinal cohort study, data were obtained from electronic health records of all U.
Introduction: Spontaneous coronary artery dissection (SCAD) is a nonatherosclerotic cause of myocardial infarction. Migraine headache has been reported to be common among patients with SCAD, but the degree of migraine-related disability has not been quantified.
Methods: Clinical data and headache variables were obtained from the baseline assessment of the prospective, multicenter iSCAD Registry.
Aim: To investigate the real-world experiences of nurses' using smart glasses to triage patients in an urgent care centre.
Design: A parallel convergent mixed-method design.
Methods: We collected data through twelve in-depth interviews with nurses using the device and a survey.
Background: Although post-traumatic stress disorder (PTSD) and depression screening are recommended for traumatic injury patients, routine screening is still uncommon. Salivary inflammatory biomarkers have biological plausibility and potential feasibility and acceptability for screening. This study tested prospective associations between several salivary inflammatory biomarkers (proinflammatory cytokines interleukin-1β, interleukin-6, tumor necrosis factor-α; and C-reactive protein), collected during hospitalization and PTSD and depressive symptoms at 5-month follow-up.
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- PTSD genetics have been difficult to study compared to other psychiatric disorders, limiting our biological understanding of the condition.
- A large-scale meta-analysis involving over 1.2 million individuals identified 95 genome-wide significant loci, with 80 being new discoveries related to PTSD.
- Researchers identified 43 potential causal genes linked to neurotransmitter activity, developmental processes, synaptic function, and immune regulation, enhancing our knowledge of the neurobiological systems involved in PTSD.
Observational studies suggest that posttraumatic stress disorder (PTSD) increases risk for various autoimmune diseases. Insights into shared biology and causal relationships between these diseases may inform intervention approaches to PTSD and co-morbid autoimmune conditions. We investigated the shared genetic contributions and causal relationships between PTSD, 18 autoimmune diseases, and 3 immune/inflammatory biomarkers.
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- Myocardial infarction from spontaneous coronary artery dissection (SCAD) can lead to significant psychological issues, including posttraumatic stress disorder (PTSD), affecting many patients' quality of life.
- In a study involving 1,156 SCAD patients, nearly 35% had experienced probable PTSD at some point, but a significant portion had not sought treatment for their symptoms.
- Factors such as younger age at first SCAD, being single, and having a history of anxiety were linked to higher PTSD symptom severity, highlighting the need for better screening and treatment connections for affected individuals.
Article Synopsis
- * The technology tracks three vital signs (pulse waveform, galvanic skin response, skin temperature) and six sweat biomarkers (glucose, lactate, etc.) for over 100 hours of stable analysis.
- * Utilizing a machine learning pipeline, the electronic skin can accurately differentiate between three types of stressors and quantify psychological stress responses with high confidence levels.
Background: Posttraumatic stress disorder (PTSD) has been associated with ischemic heart disease in women veterans, but evidence for associations with other cardiovascular disorders remains limited in this population. This retrospective longitudinal cohort study evaluated the association of PTSD with incident stroke/transient ischemic attack (TIA) in women veterans.
Methods And Results: Veterans Health Administration electronic health records were used to identify women veterans aged ≥18 years engaged with Veterans Health Administration health care from January 1, 2000 to December 31, 2019.
Article Synopsis
- The study investigates the differences in post-traumatic psychiatric disorders between males and females after experiencing potentially traumatic events (PTEs) from 1994 to 2016 in Denmark.
- It utilizes data from national health registries and compares individuals who faced PTEs with a reference group who underwent a nontraumatic stressor, focusing on the incidence of psychiatric disorders like substance use and depressive disorders.
- Findings indicate distinct patterns, with males commonly diagnosed with substance use disorders and females more often diagnosed with depressive disorders following trauma exposure.
Exercise promotes pulsatile shear stress in the arterial circulation and ameliorates cardiometabolic diseases. However, exercise-mediated metabolic transducers for vascular protection remain under-investigated. Untargeted metabolomic analysis demonstrated that wild-type mice undergoing voluntary wheel running exercise expressed increased endothelial stearoyl-CoA desaturase 1 (SCD1) that catalyzes anti-inflammatory lipid metabolites, namely, oleic (OA) and palmitoleic acids (PA), to mitigate NF-κB-mediated inflammatory responses.
View Article and Find Full Text PDFBackground: The co-design of health care enables patient-centredness by partnering patients, clinicians and other stakeholders together to create services.
Methods: We conducted a systematic review of co-designed health interventions for people living with multimorbidity and assessed (a) their effectiveness in improving health outcomes, (b) the co-design approaches used and (c) barriers and facilitators to the co-design process with people living with multimorbidity. We searched MEDLINE, EMBASE, CINAHL, Scopus and PsycINFO between 2000 and March 2022.
To improve medication adherence, we co-developed a digital, artificial intelligence (AI)-driven nudge intervention with stakeholders (patients, providers, and technologists). We used a human-centred design approach to incorporate user needs in creating an AI-driven nudge tool. We report the findings of the first stage of a multi-phase project: understanding user needs and ideating solutions.
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- - The study examines the potential of AI-supported physical rehabilitation technology to improve availability, clinical effects, and implementation barriers, addressing the growing need for rehabilitation as physical disabilities increase with age.
- - A systematic review identified 9054 articles, ultimately including 28 projects that spanned various AI solutions, such as app-based systems and robotic devices, but found inconsistent clinical outcomes from the five randomized controlled trials (RCTs) analyzed.
- - While AI in rehabilitation shows promise, challenges such as technology literacy and user fatigue hinder implementation, necessitating more rigorous clinical evaluations and real-world assessments to enhance its effectiveness.
Background: Longitudinal work on the impact of COVID-19 on population mental health and resilience beyond the first year of the pandemic is lacking. We aimed to understand how mental health and resilience evolved during the pandemic (2020) and two years later (2022) in a multi-ethnic Singaporean population. In addition, we assessed what characteristics were associated with mental health and resilience scores.
View Article and Find Full Text PDFBackground: Conventional quantitative or qualitative methodologies may not encompass the wide array of experiences of individuals living with Chronic Obstructive Pulmonary Disease (COPD). We used a novel approach - photovoice-to understand the impact of COPD on activities of daily living (ADLs) in a multicultural Asian country.
Methods: We recruited a purposive sample of eight patients from the outpatient clinics of the National University Health System, Singapore, between December 2020 and August 2021.
Article Synopsis
- Cardiovascular disease (CVD) is the top cause of death in the US, with women veterans experiencing higher mortality rates from cardiac disease compared to civilian women, highlighting the need for more research in this area.
- The study analyzed nearly two decades of data from the US Veterans Health Administration and the Centers for Disease Control and Prevention to compare cardiac disease mortality trends among women veterans and civilian women.
- Findings showed that between 2000 and 2017, over 817,000 women veterans were treated, with around 19,000 deaths from cardiac disease, accounting for a significant portion of total deaths in this population.