Publications by authors named "Jennifer Spagnolo"
Article Synopsis
- The study explores how the skin microbiota varies between individuals and seeks to understand the molecular factors behind this variability, specifically at the strain level.
- Researchers used genomics to identify a biosynthetic gene cluster in a common skin bacterium, leading to the discovery of a new antibiotic called cutimycin.
- The findings suggest that cutimycin plays a role in the skin microbiome by helping control the population of certain bacteria in human skin hair follicles.
This review provides an overview of current knowledge concerning type IVb pili in Gram-negative bacteria. The number of these pili identified is steadily increasing with genome sequencing and mining studies, but studies of these pili are somewhat uneven, because their expression is tightly regulated and the signals or regulators controlling expression need to be identified. However, as illustrated here, they have a number of interesting functional, assembly-related and regulatory features.
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