Publications by authors named "Jennifer Skerry"
Multidrug resistant organisms are a serious threat to human health. Fast, accurate antibiotic susceptibility testing (AST) is a critical need in addressing escalating antibiotic resistance, since delays in identifying multidrug resistant organisms increase mortality and use of broad-spectrum antibiotics, further selecting for resistant organisms. Yet current growth-based AST assays, such as broth microdilution, require several days before informing key clinical decisions.
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- Researchers tackled the issue of quickly identifying bacterial pathogens in infectious diseases by creating a new molecular method that uses ribosomal RNA for rapid detection without needing complicated amplification processes.
- The developed assay demonstrated over 89% accuracy in identifying specific bacterial species and 100% accuracy at the family level from a diverse group of 117 bacterial isolates.
- Initial tests using clinical samples like sputum and blood cultures effectively identified bacteria from five different phyla, showcasing its practical application in real-world situations.