Treatment of chronic lymphocytic leukemia with alemtuzumab: a review for nurses.

Purpose/objectives: To review the use of the monoclonal antibody alemtuzumab in patients with advanced refractory B cell chronic lymphocytic leukemia (B-CLL) and nursing management during treatment.

Data Sources: Published articles, abstracts, book chapters, Web sites, and training material.

Data Synthesis: Alemtuzumab can achieve disease remission in patients with chemorefractory B-CLL; however, management of high-risk patients presents certain challenges.