Impact of Lesion Placement on Efficacy and Safety of Catheter-Based Radiofrequency Renal Denervation.

Background: Insufficient procedural efficacy has been proposed to explain nonresponse to renal denervation (RDN).

Objectives: The aim of this study was to examine the impact of different patterns of lesion placements on the efficacy and consistency of catheter-based radiofrequency RDN in pigs.

Methods: The impact of increasing number of lesions versus location of RDN was investigated in a porcine model (Group 1; n = 51).

Efficacy and safety of catheter-based radiofrequency renal denervation in stented renal arteries.

Background: In selected patients with hypertension, renal artery (RA) stenting is used to treat significant atherosclerotic stenoses. However, blood pressure often remains uncontrolled after the procedure. Although catheter-based renal denervation (RDN) can reduce blood pressure in certain patients with resistant hypertension, there are no data on the feasibility and safety of RDN in stented RA.