Publications by authors named "Jennifer R Jorgensen"

Article Synopsis
  • Scar tissue formation is a critical part of wound healing but can disrupt tissue function, particularly in cases like uterine scarring from cesarean sections.
  • The research focused on how deep uterine scars contribute to a condition called placenta accreta spectrum (PAS), where invasive cells can lead to serious complications during pregnancy.
  • The study found that scar tissue activates the mechanosensitive ion channel, Piezo1, which triggers inflammatory pathways and draws invasive cells towards the scar, highlighting how scar mechanics can disturb normal tissue interactions and potentially relate to cancer spread.
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Neuroendocrine neoplasms commonly arise from the gastrointestinal tract and lungs. Less commonly, they may occur in the gynecologic tract, typically within the ovary of a mature cystic teratoma. Primary neuroendocrine neoplasms of the fallopian tube are exceptionally rare and only a total of 11 cases have been reported in the literature.

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Article Synopsis
  • * Data from 217 patients revealed that factors like body mass index, hypertension, race, and aspirin use were predictive of readmission, with significant differences in disease-free and overall survival between those admitted and those who were not.
  • * The findings suggest that readmission rates in this population were higher than previously reported, highlighting the need to identify at-risk patients to improve chemotherapy planning and resource allocation for patient care.
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Objective: To investigate whether the 2006 American Society for Colposcopy and Cervical Pathology guidelines for conservative management of minimally abnormal Pap test results (atypical squamous cells of undetermined significance, human papillomavirus-positive, and low-grade squamous intraepithelial lesions) and moderate dysplasia (cervical intraepithelial neoplasia 2) in adolescents 1) resulted in fewer colposcopies and loop electrosurgical excision procedures (LEEPs) in adolescents or 2) resulted in unintended treatment changes in older age groups.

Methods: We analyzed data from 1,806 women aged 18 years and older attending one of six community health centers who were diagnosed with abnormal Pap test results between January 1, 2004, and December 31, 2008. We used multivariable logistic regression to examine treatment differences in women with minimally abnormal Pap test results before and after guideline changes.

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