Publications by authors named "Jennifer R Evans"

Article Synopsis
  • Cataracts are a leading cause of blindness and are often treated with surgery to remove the cloudy lens and replace it with an artificial one, usually made of hydrophobic acrylic.
  • Recent advancements in intraocular lens (IOL) technology have introduced options like trifocal and extended depth of focus (EDOF) lenses, which aim to enhance vision across all distances and reduce reliance on glasses.
  • The study aims to compare the visual outcomes of trifocal IOLs with EDOF IOLs in adults after cataract surgery and includes an examination of economic evaluations related to these lens types.
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Objectives: In pursuit of health equity, the World Health Organization has recently called for more extensive monitoring of inequalities in eye health. Population-based eye health surveys can provide this information, but whether underserved groups are considered in the design, implementation, and reporting of surveys is unknown. We conducted a systematic methodological review of surveys published since 2000 to examine how many population-based eye health surveys have considered underserved groups in their design, implementation, or reporting.

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Background: Uncorrected refractive error is a leading cause of vision impairment which, in most cases, can be managed with the appropriate spectacle correction. In 2021, the World Health Assembly endorsed a global target of a 40-percentage-point increase in effective coverage of refractive error by 2030. To achieve this global target, equitable access to refractive and optical services within community and primary care settings needs to be strengthened.

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Introduction: Glaucoma is the leading cause of irreversible blindness in the world. The need to diagnose glaucoma early in its natural history before extensive sight loss occurs cannot be overemphasised. However, glaucoma is largely asymptomatic in the early stages of the disease making it complex to diagnose clinically and requires the support of technology.

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Background: Age-related macular degeneration (AMD) is a degenerative condition of the back of the eye that occurs in people over the age of 50 years. Antioxidants may prevent cellular damage in the retina by reacting with free radicals that are produced in the process of light absorption. Higher dietary levels of antioxidant vitamins and minerals may reduce the risk of progression of AMD.

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Diabetic retinopathy (DR) is a leading cause of blindness globally. There is growing evidence to support the use of artificial intelligence (AI) in diabetic eye care, particularly for screening populations at risk of sight loss from DR in low-income and middle-income countries (LMICs) where resources are most stretched. However, implementation into clinical practice remains limited.

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Unlabelled: In pursuit of Universal Health Coverage (UHC) for eye health, countries must strengthen services for older adults, who experience the highest prevalence of eye conditions. This scoping review narratively summarised (i) primary eye health services for older adults in eleven high-income countries/territories (from government websites), and (ii) the evidence that eye health services reduced vision impairment and/or provided UHC (access, quality, equity, or financial protection) (from a systematic literature search). We identified 76 services, commonly comprehensive eye examinations ± refractive error correction.

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Background: Cataract is the leading cause of blindness in the world and, as such, cataract surgery is one of the most commonly performed operations globally. Surgical techniques have changed dramatically over the past half century with associated improvements in outcomes and safety. Femtosecond lasers can be used to perform the key steps in cataract surgery, such as corneal incisions, lens capsulotomy and fragmentation.

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Article Synopsis
  • The WHO is creating a Package of Eye Care Interventions (PECI) to integrate eye care into universal health coverage, focusing on evidence-based practices for uveitis from clinical practice guidelines (CPGs).
  • A systematic review identified 56 potentially relevant CPGs on uveitis from 2010 to March 2020, but only 3 CPGs met the criteria for data extraction after appraising their quality with the AGREE II tool.
  • The reviewed CPGs addressed specific aspects of uveitis treatment and management, but there is limited guidance available, reflecting the complexity of uveitis, which may hinder clinicians looking for effective care strategies.
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Article Synopsis
  • * A scoping review revealed 183 reports from 153 studies, mostly from high-income countries, indicating that DSI prevalence increases with age and is linked to poorer psychosocial, participation, and physical health outcomes compared to individuals with one or no impairments.
  • * The review highlights significant knowledge gaps around DSI, particularly in lower-income countries, and stresses the need for standardized definitions and reporting to improve understanding and services.
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Background: Diabetic retinopathy (DR) is characterised by neurovascular degeneration as a result of chronic hyperglycaemia. Proliferative diabetic retinopathy (PDR) is the most serious complication of DR and can lead to total (central and peripheral) visual loss. PDR is characterised by the presence of abnormal new blood vessels, so-called "new vessels," at the optic disc (NVD) or elsewhere in the retina (NVE).

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Importance: Despite persistent inequalities in access to eye care services globally, guidance on a set of recommended, evidence-based eye care interventions to support country health care planning has not been available. To overcome this barrier, the World Health Organization (WHO) Package of Eye Care Interventions (PECI) has been developed.

Objective: To describe the key outcomes of the PECI development.

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Background: This systematic review assessed the effectiveness of universal screening for newborn eye abnormalities compared with no screening in improving infant vision and health outcomes.

Methods: We searched CENTRAL (Cochrane Library), MEDLINE, Embase, Global Health, Global Index Medicus, clinical trials databases, and bibliographies of relevant articles. We included randomized and observational studies of all newborns, regardless of illness or risk factors, that compared universal screening for any eye abnormality by eight weeks of age with no universal screening.

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Article Synopsis
  • Cataracts are the top cause of blindness worldwide, and effective cataract surgical coverage (eCSC) is crucial to gauge the success of surgical interventions across different populations.
  • The World Health Assembly aims to increase eCSC by 30 percentage points by 2030, prompting the analysis of existing survey data to establish a baseline for this metric.
  • Findings show significant disparities in eCSC among countries, with high-income nations having better access and outcomes compared to low-income ones, and men generally experiencing higher eCSC than women.
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Background: Open-angle glaucoma (OAG) is an important cause of blindness worldwide. Laser trabeculoplasty, a treatment modality, still does not have a clear position in the treatment sequence.

Objectives: To assess the effects of laser trabeculoplasty for treating OAG and ocular hypertension (OHT) when compared to medication, glaucoma surgery or no intervention.

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Diabetic retinopathy is a leading cause of vision loss globally. The current diagnostic thresholds for diabetes are still based on historic data correlating glycemic parameters with retinopathy; however, an excess prevalence of retinopathy has also been reported in prediabetes. We aimed to determine the reported prevalence of retinopathy in adults with prediabetes.

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Article Synopsis
  • UN member states aim to achieve the Sustainable Development Goals (SDGs) by 2030, and this Review explores how improving eye health can help meet these goals beyond just health-related targets.* -
  • The analysis identified 29 studies demonstrating that eye health services, like cataract surgery and community eye health initiatives, positively impact various SDGs related to poverty, education, equality, and sustainable cities.* -
  • The Review suggests that while eye health services have clear direct benefits for some SDGs, they may also indirectly influence others, and there are potential connections to additional SDGs that need further investigation.*
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Purpose: The World Health Organization is developing a Package of Eye Care Interventions (PECI) to support the integration of eye health care into national health programmes. Interventions included in the PECI should be based on robust evidence where available. Refractive error is a leading cause of blindness and vision impairment and is a PECI priority condition.

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Purpose: The World Health Organization's Package of Eye Care Interventions (PECI) aims to support incorporation of amblyopia detection and treatment into health service provision. The aim of this study was to systematically review clinical practice guidelines (CPGs) for amblyopia to inform the development of this package.

Methods: MEDLINE, Embase, CINAHL and Global Index Medicus databases, guideline databases and professional body websites were searched for CPGs published in English between 2010 and 9th March 2020.

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Objective: To conduct a systematic review to identify and critically appraise clinical practice guidelines on the assessment, diagnosis and management of childhood glaucoma.

Methods And Analysis: A systematic literature search of databases and professional websites for clinical practice guidelines published on eye conditions between 2010 and April 2020 in English was conducted. Identified guidelines were screened for relevance to childhood glaucoma and exclusion criteria applied.

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Background: We undertook a Grand Challenges in Global Eye Health prioritisation exercise to identify the key issues that must be addressed to improve eye health in the context of an ageing population, to eliminate persistent inequities in health-care access, and to mitigate widespread resource limitations.

Methods: Drawing on methods used in previous Grand Challenges studies, we used a multi-step recruitment strategy to assemble a diverse panel of individuals from a range of disciplines relevant to global eye health from all regions globally to participate in a three-round, online, Delphi-like, prioritisation process to nominate and rank challenges in global eye health. Through this process, we developed both global and regional priority lists.

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Purpose: People who are distinct from the dominant ethnic group within a country can experience a variety of barriers to accessing eyecare services. We conducted a scoping review to map published interventions aimed at improving access to eyecare for non-Indigenous, non-dominant ethnic groups residing in high-income countries.

Methods: We searched MEDLINE, Embase and Global Health for studies that described an intervention to promote access to eyecare for the target population.

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Background: Posterior capsule opacification (PCO) is a clouding of the posterior part of the lens capsule, a skin-like transparent structure, which surrounds the crystalline lens in the human eye. PCO is the most common postoperative complication following modern cataract surgery with implantation of a posterior chamber intraocular lens (IOL). The main symptoms of PCO are a decrease in visual acuity, 'cloudy', blurred vision and reduced contrast sensitivity.

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Article Synopsis
  • Cochrane Eyes and Vision (CEV) is a global group that creates reviews to help treat and prevent eye diseases and vision problems.
  • They plan to figure out which research questions are most important by getting input from different people involved in eye care.
  • The study has been approved by an ethics committee and they will share their findings through various channels including research journals.
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