Utilization of a Dextrose-Only Purge Solution for an LVAD in Patients With Suspected HIT: A Case Series.

The Impella devices are percutaneous intravascular ventricular assist devices indicated for use in patients with cardiogenic shock that occurs following acute myocardial infarction (MI) or open heart surgery. These devices must be used with a purge solution that contains heparin per manufacturer recommendation, which will prevent blood from reaching the motor causing pump thrombosis and mechanical failure. We describe the utilization of a dextrose-only purge solution plus systemic argatroban in 2 patients with suspected heparin-induced thrombocytopenia (HIT).

Diversity of amino acid substitutions in PmrCAB associated with colistin resistance in clinical isolates of Acinetobacter baumannii.

This study aimed to investigate the mechanisms of colistin resistance in 64 Acinetobacter baumannii isolates obtained from patients with ventilator-associated pneumonia hospitalised in Greece, Italy and Spain. In total, 31 A. baumannii isolates were colistin-resistant.

Investigation of Novel and Mutations in Isogenic Acinetobacter baumannii Isolates Associated with Colistin Resistance and Increased Virulence .

Colistin resistance in is of great concern and is a threat to human health. In this study, we investigate the mechanisms of colistin resistance in four isogenic pairs of isolates displaying an increase in colistin MICs. A mutation in was detected in each colistin-resistant isolate, three of which were novel (A28V, I232T, and ΔL9-G12).

Diversity of mutations in regulatory genes of resistance-nodulation-cell division efflux pumps in association with tigecycline resistance in Acinetobacter baumannii.

Objectives: To investigate the mechanisms of tigecycline resistance in isogenic Acinetobacter baumannii isolate pairs as well as 65 unique clinical A. baumannii isolates obtained during the MagicBullet clinical trial from Greece, Italy and Spain.

Methods: A.

Constrained posture in dentistry - a kinematic analysis of dentists.

Background: How a dentist works, such as the patterns of movements performed daily, is also largely affected by the workstation Dental tasks are often executed in awkward body positions, thereby causing a very high degree of strain on the corresponding muscles. The objective of this study is to detect those dental tasks, during which awkward postures occur most frequently. The isolated analysis of static postures will examine the duration for which these postures are maintained during the corresponding dental, respectively non-dental, activities.

Restricted posture in dentistry - a kinematic analysis of orthodontists.

Background: This study aims at identifying orthodontic activities with the highest frequency of unfavorable/awkward and static postures held over a period of more than 4 s based on kinematic analysis. Moreover, a separate analysis of static postures for orthodontic and non-orthodontic activities serves to evaluate the duration for which these particular postures are assumed.

Methods: In total, 21 (13f/8 m) orthodontists (age: 31.

Kinematic analysis of work-related musculoskeletal loading of trunk among dentists in Germany.

Background: In Germany, about 86.7 % of the dentists have stated to suffer from pain in the neck and shoulder region. These findings are predominantly based on surveys.

The Asp20-to-Asn Substitution in the Response Regulator AdeR Leads to Enhanced Efflux Activity of AdeB in Acinetobacter baumannii.

Overexpression of the resistance-nodulation-cell division-type efflux pump AdeABC is often associated with multidrug resistance in Acinetobacter baumannii and has been linked to mutations in the genes encoding the AdeRS two-component system. In a previous study, we reported that the Asp20→Asn amino acid substitution in the response regulator AdeR is associated with adeB overexpression and reduced susceptibility to the antimicrobials levofloxacin, tigecycline, and trimethoprim-sulfamethoxazole. To further characterize the effect of the Asp20→Asn substitution on antimicrobial susceptibility, the expression of the efflux genes adeB, adeJ, and adeG, and substrate accumulation, four plasmid constructs [containing adeR(Asp20)S, adeR(Asn20)S, adeR(Asp20)SABC, and adeR(Asn20)SABC] were introduced into the adeRSABC-deficient A.

Prevalence of eight resistance-nodulation-division efflux pump genes in epidemiologically characterized Acinetobacter baumannii of worldwide origin.

The increasing emergence of multidrug-resistant Acinetobacter baumannii constitutes a worldwide threat in hospital settings. Efflux-mediated resistance, particularly the resistance-nodulation-division (RND)-type efflux pumps, contributes significantly to decreased susceptibility to multiple antibiotics when overexpressed. Using PCR-based detection, the prevalence of genes encoding the RND efflux pumps AdeB, AdeJ and AdeG was investigated amongst 144 epidemiologically characterized and geographically diverse A.

Multiresolution wavelet analysis of time-dependent physiological responses in syncopal youths.

Our prior studies indicated that postural fainting relates to thoracic hypovolemia. A supranormal increase in initial vascular resistance was sustained by increased peripheral resistance until late during head-up tilt (HUT), whereas splanchnic resistance, cardiac output, and blood pressure (BP) decreased throughout HUT. Our aim in the present study was to investigate the alterations of baroreflex activity that occur in synchrony with the beat-to-beat time-dependent changes in heart rate (HR), BP, and total peripheral resistance (TPR).

A comparison of head movement during back boarding by motorized spine-board and log-roll techniques.

Context: In a patient with a potential cervical spine injury, minimizing or eliminating movement at the head and neck during stabilization and transport is paramount because movement can exacerbate the condition. Any equipment or technique creating less movement will allow for a more effective and safe stabilization of an injured patient, reducing the likelihood of movement and potential secondary injury.

Objective: To compare the amount of head movement created during the log-roll and motorized spine-board (MSB) stabilization techniques.

Construct validity and reliability of the College Oriented Eating Disorders Screen (COEDS).

The College Oriented Eating Disorders Screen [COEDS; Nowak, J.A., Roberson-Nay, R.

An analogue investigation of the relationships among perceived parental criticism, negative affect, and borderline personality disorder features: the role of thought suppression.

The current study examined the relationships among biological predisposition, social environment, emotion regulation, and features characteristic of Borderline Personality Disorder (BPD). Using an analogue sample, we examined whether thought suppression mediated the relationship of negative affective intensity/reactivity and perceived parental criticism with a composite of BPD features including impulsivity, interpersonal sensitivity, and aggression. Results indicated that thought suppression fully mediated the relationship between negative affect intensity/reactivity and BPD features and partially mediated the relationship between BPD features and perceived parental criticism.

Using item response theory in the development and validation of the College-Oriented Eating Disorders Screen.

The current study examined the psychometric characteristics of the College-Oriented Eating Disorders Screen (COEDS), a college-student-focused screening measure to assess and identify individuals at-risk for the development of eating disordered pathology. By screening a large pool of pilot questions and using methods based in item response theory (IRT), seven items were identified with well-targeted contents that discriminated well across the continuum of eating disorder severity. The resulting measure evidenced a unidimensional factor structure and correlated highly with the original COEDS, standard measures of eating disorders pathology, and a measure of associated symptomatology (e.

Examining the inventory of interpersonal problems as a tool for conducting analogue studies of mechanisms underlying Borderline Personality Disorder.

Despite recent advancements in the treatment of Borderline Personality Disorder (BPD), little is known about the underlying mechanisms in the development and maintenance of the disorder. To examine these issues, it is first necessary to identify a brief screening measure that can be used to assess factors underlying BPD. Considering this need, the current investigation examined the utility of a BPD-related composite consisting of the Inventory of Interpersonal Problems-Interpersonal Sensitivity (IIP-IS) and Aggression (IIP-Ag) subscales of the IIP in a sample of college students ( [Formula: see text] ) and a sample of individuals seeking residential drug use treatment ( [Formula: see text] ).