Cognitive impairment, behavioral impairment, depression, and wish to die in an ALS cohort.

Objective: To evaluate relationships among cognitive, behavioral, and psychiatric/psychosocial measures assessed in a multicenter cohort of patients with amyotrophic lateral sclerosis (ALS).

Methods: Recently diagnosed patients with definite or probable ALS diagnosis were administered 7 standardized psychiatric/psychosocial measures, including the Patient Health Questionnaire for diagnosis of depression and elicitation of wish to die. The Cognitive Behavioral Screen was used to classify both cognitive and behavioral impairment (emotional-interpersonal function).

Magnetic resonance imaging volumetric analysis of the putamen in children with ADHD: combined type versus control.

Objective: Volumetric differences in the putamen of boys with ADHD combined subtype with psychopathic traits and controls are investigated.

Method: The putamen in 24 archival magnetic resonance imaging scans of 12 boys in residential treatment with symptoms of ADHD and psychopathic traits and 12 community control boys are analyzed using Display software.

Results: There are no differences found in the total, left, and right putamen volumes across the ADHD or control group.