Development of a High-Fidelity Simulator for Teaching Chorionic Villus Sampling.

Objective: The objective of this study was to develop a synthetic high-fidelity simulator for teaching chorionic villus sampling.

Methods: Working with a medical sculptor, the authors developed a simulator, constructed from various synthetic rubber materials, of a gravid female pelvis, including the vulva, vagina, cervix, and a 13-week-sized uterus with a gestational sac.

Results: This simulator is high fidelity and durable, and it does not require any organic materials.

Comparison of pain during two methods of urine collection in preterm infants.

Background: Suprapubic aspiration (SPA) and urine catheterization (UC) are performed frequently in preterm neonates to rule out urinary tract infection; however, a comparison of the pain caused by both procedures has not been made previously.

Objective: To compare pain responses in preterm infants who are undergoing urine collection by using SPA versus UC.

Methods: Prospective, single-blind, randomized clinical trial was conducted in 2 NICUs.

Routine immunization practices: use of topical anesthetics and oral analgesics.

Background: Immunization pain is a global public health issue. Despite an abundance of data that demonstrate the efficacy of local anesthetics for decreasing immunization pain, their adoption in practice has not been determined. Our objective was to evaluate analgesic use during childhood immunization.

Acetaminophen and ibuprofen for prevention of adverse reactions associated with childhood immunization.

Objective: To evaluate the literature examining prophylactic use of acetaminophen and ibuprofen for prevention of adverse reactions associated with childhood immunization.

Data Sources: Articles were identified via MEDLINE/PubMed/EMBASE (1966-March 2007) using the following key terms: vaccination, immunization, diphtheria-tetanus toxoids-whole pertussis (DTwP), diphtheria tetanus-toxoid, whole pertussis, diphtheria-tetanus toxoids-acellular pertussis (DTaP), acellular pertussis, Haemophilus influenzae type B, inactivated poliovirus, pneumococcal 7-valent conjugate, measles, mumps, rubella, meningococcal C-conjugate, varicella zoster, hepatitis B, influenza, pneumococcal polysaccharide, adverse reactions, analgesics, antipyretics, acetaminophen, ibuprofen, infant, and child.

Study Selection And Data Extraction: No limitations were placed on article selection.

Quality and content of abstracts in papers reporting about drug exposures during pregnancy.

Background: Most clinicians read only the abstract of papers in scientific journals. Therefore, it is very important that abstracts contain as much information as possible, to summarize the data succinctly. Our objectives were to evaluate the quality of information in abstracts reporting human fetal outcomes following drug exposure during pregnancy.