Publications by authors named "Jennifer Karume Gutierrez-Galicia"
Article Synopsis
- The study examines how stress affects gut health, focusing on goblet cells and inflammation in different small intestine regions of mice.
- Female 8-week-old BALB/c mice were subjected to board immobilization stress, leading to changes in mucin levels and IgA-microbiota complexes in the small intestine.
- Results indicated increased inflammation in the proximal small intestine due to stress, potentially linking these findings to conditions like Crohn's disease in humans.
Background: Microbiota and tight junction proteins (TJPs) are components of the gut barrier, and are considered stress targets that have deleterious effects on intestinal homeostasis.
Objectives: This study aimed to evaluate the effects of chronic immobilization stress on selected small intestine homeostasis parameters.
Material And Methods: Female BALB/c mice were divided into a stress group that underwent short-term immobilization for 2 h per day for 4 consecutive days, and a non-stressed control group (n = 6 per group).