Initiatives to Address Diversity, Equity, and Inclusion Within a Higher Education ABA Department.

Recent events have highlighted the need for behavior analysis to address issues of diversity, equity, and inclusion (DEI) in service provision and in higher education. There has been a call to action issued, noting the need for cultural humility and cultural responsiveness. An opportunity exists within training programs to ensure that students of behavior analysis are instructed in ways that promote cultural responsiveness and that equip them to serve diverse populations.

Behavioral Treatment of Self-Injury: 2001 to 2016.

Individuals diagnosed with intellectual and developmental disabilities (IDD) frequently exhibit self-injurious behavior (SIB). Previous research has examined the published literature on behavioral treatments of SIB from 1964-2000. Results suggested that these treatments were highly efficacious at decreasing SIB, particularly when based on the results of a functional assessment.

Effect of endometrial injury on in vitro fertilization pregnancy rates: a randomized, multicentre study.

Purpose: To determine if endometrial injury prior to the first or second in vitro fertilization (IVF) cycle affects clinical pregnancy rates.

Methods: This study was a randomized, multicentre, controlled study performed at three Canadian outpatient fertility clinics. Patients undergoing their first or second IVF cycle were randomized to a single endometrial injury 5-10 days prior to the start of gonadotropins in an IVF cycle compared to no injury.

Antagonism of substance P and perception of breathlessness in patients with chronic obstructive pulmonary disease.

The objective of this study was to investigate whether substance P, an excitatory neuropeptide, modulates the perception of breathlessness by administering aprepitant, a selective antagonist that blocks neurokinin (NK)-1 receptor signaling. Individual targeted resistive load breathing (RLB) was used to provoke breathlessness. In Study 1, sixteen patients (age, 70±6 years) with chronic obstructive pulmonary disease (COPD) reported similar ratings of breathlessness during RLB between oral aprepitant (125mg) and placebo.

A reduction in Ptprq associated with specific features of the deafness phenotype of the miR-96 mutant mouse diminuendo.

miR-96 is a microRNA, a non-coding RNA gene which regulates a wide array of downstream genes. The miR-96 mouse mutant diminuendo exhibits deafness and arrested hair cell functional and morphological differentiation. We have previously shown that several genes are markedly downregulated in the diminuendo organ of Corti; one of these is Ptprq, a gene known to be important for maturation and maintenance of hair cells.

Exome sequencing identifies a missense mutation in Isl1 associated with low penetrance otitis media in dearisch mice.

Background: Inflammation of the middle ear (otitis media) is very common and can lead to serious complications if not resolved. Genetic studies suggest an inherited component, but few of the genes that contribute to this condition are known. Mouse mutants have contributed significantly to the identification of genes predisposing to otitis media

Results: The dearisch mouse mutant is an ENU-induced mutant detected by its impaired Preyer reflex (ear flick in response to sound).

miR-96 regulates the progression of differentiation in mammalian cochlear inner and outer hair cells.

MicroRNAs (miRNAs) are small noncoding RNAs able to regulate a broad range of protein-coding genes involved in many biological processes. miR-96 is a sensory organ-specific miRNA expressed in the mammalian cochlea during development. Mutations in miR-96 cause nonsyndromic progressive hearing loss in humans and mice.

Intravenous nitroglycerin for external cephalic version: a randomized controlled trial.

Objective: To estimate whether treatment with intravenous nitroglycerin for uterine relaxation increases the chance of successful external cephalic version.

Methods: Two double-blind, randomized clinical trials were undertaken: one in nulliparous women and a second in multiparous women. Women presenting for external cephalic version at term were eligible to participate.

Multifocal multi-site Warthin tumour.

The unique case of a 55-year-old man with multifocal adenolymphoma (Warthin's tumour) of both parotid glands, the neck and post-nasal space is presented. Warthin tumour is almost exclusively a parotid tumour but is known to be bilateral in 7-10% of cases and multifocal in 2% of cases. Most extraglandular Warthin tumours have been located in neck lymph nodes and only a few cases have been reported from other sites.

Magnetic resonance image attributes of the bovine corpus luteum during development and regression.

To determine whether magnetic resonance (MR) image attributes of the corpus luteum (CL) reflect its physiologic status at different phases of the bovine ovarian cycle, we analyzed the numerical pixel values (NPVs), relaxation rates, proton densities (PDs), and apparent diffusion coefficients (ADCs) from T(1)-, T(2)-, and diffusion-weighted in vitro images and maps of the CL acquired at defined phases of luteal function. Ovaries were removed and serum samples taken on days 3, 6, and 10, or >/=17 (day 0 = ovulation), representing metestrus (n = 10), early diestrus (n = 7), mid-diestrus (n = 9), and proestrus (n = 7), respectively. Regions of interest (ROIs) in each quadrant of the CL (which occupied at least 20% of the quadrant) were selected for analysis.