Rethinking bomb threat response.

Understanding the explosive threat landscape is paramount to having a sound evacuation protocol. Security procedures and response to threats can no longer be static and uniformly applied; rather, they must be tailored to ever-evolving terrorist and criminal tactics. This paper introduces recent statistics regarding the decreasing number of domestic bombings in the USA.

SIRT1 Mediates Depression-Like Behaviors in the Nucleus Accumbens.

Unlabelled: Depression is a recurring and life-threatening illness that affects up to 120 million people worldwide. In the present study, we show that chronic social defeat stress, an ethologically validated model of depression in mice, increases SIRT1 levels in the nucleus accumbens (NAc), a key brain reward region. Increases in SIRT1, a well characterized class III histone deacetylase, after chronic social defeat suggest a role for this enzyme in mediating depression-like behaviors.