Publications by authors named "Jennifer Gerdts"

Article Synopsis
  • The review covers the genetic and epigenetic factors related to food allergies, including their inheritance and the advantages and limitations of study methods.
  • Genome-wide association studies have identified 16 significant genetic variants linked to food allergies, often overlapping with other allergic conditions.
  • The article emphasizes the importance of integrating genetic and epigenetic data for understanding disease mechanisms and suggests future implications for predicting food allergy risks and responses to treatment.
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This Anaphylaxis Manifesto calls on communities to prioritise 10 practical actions to improve the lives of people at risk of serious allergic reactions. The Global Allergy and Asthma European Network and the European Federation of Allergy and Airways Diseases Patients' Associations (EFA) compiled patient-centric priorities. We used qualitative consensus methods, research evidence and feedback from over 200 patient groups, stakeholder organisations and healthcare professionals.

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Introduction: Anaphylaxis is an acute life-threatening allergy, most commonly provoked by food, venom, or drugs. There is limited data regarding differences in symptomatology between anaphylaxis provoked by different triggers. This study aimed to assess sociodemographic characteristics, clinical symptoms, and management of anaphylaxis, according to triggers in adults.

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Article Synopsis
  • IgE-mediated food allergies are the most common type, causing quick and serious reactions that affect patients' and caregivers' lives.
  • Omalizumab is a humanized monoclonal antibody that binds to IgE, reducing allergic reactions, and has been approved by the FDA for treating these food allergies.
  • The GALEN ANACARE Consensus Statement supports omalizumab's use based on a systematic review and expert agreement, noting it is currently the only drug that can significantly reduce IgE-mediated food allergic reactions, although more evidence is needed for stronger guideline recommendations.
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Article Synopsis
  • Precautionary Allergen Labelling (PAL) is used to warn people about possible allergens in food that could affect those with allergies.
  • The World Allergy Organization found that PAL is not consistently regulated, which makes it confusing for people with food allergies.
  • There are discussions among global organizations to create better rules for PAL so that it is clear and helpful for everyone, but there are still some challenges to making these rules work everywhere.
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Background: Previous guidelines recommend prompt epinephrine administration, followed by observation in the emergency department (ED). The need for transfer in all cases of anaphylaxis has recently been challenged.

Objective: To evaluate the need for additional ED treatment among children with anaphylaxis who received prehospital epinephrine.

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Article Synopsis
  • Households managing food allergies, particularly dairy allergies in young children, experience higher food costs and challenges with food security, prompting the development of a specialized food supplement program.
  • A pilot program in Winnipeg provided eight families with biweekly deliveries of allergen-friendly foods, aimed at assessing impacts on food costs, security, and caregiver mental health over six months.
  • Findings showed a slight increase in direct food costs but a significant reduction in indirect costs, specifically costs associated with lost time due to food allergy management, although overall food security and caregiver well-being saw minimal changes.
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() is a telementoring learning model to increase community capacity for autism-related health care. Seventy-seven pediatric providers (mostly primary care, seeing exclusively Medicaid patient populations) enrolled in 1 year of . Analysis of self-report surveys showed a significant increase in autism diagnoses made by ECHO providers after 1 year, (1, 65) = 7.

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Background: Egg is the third most common food allergy in children; however, data on pediatric egg-induced anaphylaxis are sparse.

Objective: To describe the clinical characteristics, management, and outcomes of pediatric egg-induced anaphylaxis.

Methods: Children presenting with anaphylaxis were recruited from 13 emergency departments as part of the Cross-Canada Anaphylaxis Registry, from which data on anaphylaxis triggered by egg were extracted.

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Article Synopsis
  • Cow's milk is a prevalent allergen in children, causing about 10% of anaphylactic reactions, and can lead to severe health risks.
  • Data from 2011 to 2023 showed that prehospital epinephrine use can lower the need for multiple doses in the emergency department, particularly among younger children.
  • The study highlights that children under 5 often have milder reactions compared to older kids, with symptoms like wheezing and vomiting being more common in milk-induced cases than with other food allergies.
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Article Synopsis
  • Epinephrine is really important for treating severe allergic reactions called anaphylaxis, but many people are using other medicines like antihistamines and steroids instead.
  • A study looked at how these different treatments worked by collecting information from thousands of patients with anaphylaxis in Canada and Israel.
  • The results showed that using epinephrine before getting to the hospital helped reduce serious problems during the allergic reaction, while antihistamines also seemed to help, but steroids made patients need more fluids when they arrived at the emergency room.
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The market share of foods carrying labels suggesting absence of animal ingredients has significantly increased in recent years. The purpose of this study was to document the purchasing behaviour of egg- or milk-allergic consumers vis-à-vis food marketed as "vegan" and "plant-based", and to evaluate the associated allergenic risk. A survey was conducted among egg- and milk-allergic consumers and revealed that 86% (margin of error 5.

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Anaphylaxis has occurred in preschools/schools yet there are no consistent food allergy (FA) management practices in early learning and childcare centres (ELCC) across jurisdictions. Presently, there are no reviews that have synthesized FA-related knowledge and management practices within ELCC. We aimed to perform a scoping review of FA management in ELCC, and report on perceived gaps or barriers.

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To assess knowledge of Canadian dietitians on the topics of food allergy and food allergy prevention guidelines, including introduction of allergenic solids to infants at risk of food allergy. An online survey was distributed via email listservs targeting Canadian dietitians. In total, 144 of 261 dietitians completed the survey (60.

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Background: Children with food allergy, and their families experience substantial burdens because of efforts necessary to minimize the risk of anaphylaxis. To this end, peer-to-peer education is paramount. Food Allergy Canada offers an online, peer-to-peer mentoring program.

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Background: Pediatric food allergy is associated with excess familial food costs compared to families without allergy. Since the start of the COVID-19 pandemic, food prices have increased substantially.

Objective: To understand the temporal pattern of food insecurity amongst Canadian families with food allergy from the year prior to the pandemic, through May 2022.

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For food-allergic patients, hypoallergenic formulas (HFs) are medically indicated, often a primary component of the diet and essential for patient safety, health, nutrition, and overall well-being. Yet, food allergy is not included among the conditions mandated for coverage under federal health programs and private health insurance. The 2022 infant formula crisis has affected many North American families and has particularly influenced patients with food allergies who rely on a limited number of safe HF brands to safely meet their nutritional needs for growth and development.

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Article Synopsis
  • There is currently no consensus on how to define and categorize the severity of food allergies, despite the existence of various scoring systems for anaphylactic reactions.
  • The aim of this study was to develop a global scoring system, called DEFASE, that comprehensively assesses food allergy severity using input from international experts.
  • The results showed strong agreement among experts on key components of the DEFASE score through a structured survey, marking it as the first comprehensive grading that considers the overall disease spectrum, not just individual reactions.
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Background: Anaphylaxis is an acute systemic and potentially fatal allergic reaction. We evaluated trends in yearly rates of anaphylaxis in a pediatric Emergency Department (ED) in Montreal, Canada.

Methods: A prospective and retrospective recruitment process was used to find families of children who had presented with anaphylaxis at the Montreal Children's Hospital between April 2011 and April 2021.

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We aimed to develop and test the effectiveness of an education tool to help pediatric patients and their families better understand anaphylaxis and its management, and to improve current knowledge and treatment guidelines adherence. From June 2019 to May 2022, 128 pediatric patients with history of food-triggered anaphylaxis who presented to the allergy outpatient clinics at the study institution were recruited. Consenting families were asked to complete 6 questions related to the triggers, recognition, and management of anaphylaxis at the time of presentation to the clinic.

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Canadian regulations require food business operators (FBOs) to implement preventive controls to manage allergens and ensure their accurate declaration. However, the use of precautionary allergen labelling (PAL) is voluntary and competent authorities provide limited guidance on its use. The objective of this study was to present an overview of Canadian FBOs' current allergen management practices, including the mechanisms used to evaluate the need for PAL in finished products, and to investigate potential areas for improvement.

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This paper describes a proposed model of diagnostic evaluation for autism spectrum disorder (ASD) at a large-scale ASD specialty center. Our center has implemented age-based diagnostic tracks within an interdisciplinary team evaluation approach to assessing ASD. Data were collected as part of a program evaluation and included responses from provider surveys as well as patient medical record reviews.

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