Publications by authors named "Jennifer E Ryba"
Article Synopsis
- Observational studies indicate a potential increased risk of kidney damage (nephrotoxicity) when combining piperacillin-tazobactam with vancomycin, though results are mixed.
- A meta-analysis was conducted involving six studies with a total of 963 patients to evaluate the nephrotoxicity risk of this combination compared to controls.
- The findings suggest that adding piperacillin-tazobactam to vancomycin significantly raises the risk of nephrotoxicity, but no significant differences were observed in the need for renal replacement therapies among the groups.
