Publications by authors named "Jennifer E Brondon"
Article Synopsis
- Ceroid lipofuscinosis neuronal (CLN) is a rare neurodegenerative disorder that affects children, causing issues like epilepsy, vision loss, and early death.
- A study analyzed 8 patients with different types of CLN who underwent umbilical cord blood transplant (UCBT) between 2012 and 2020, finding that all patients had successful donor cell engraftment without severe transplant-related deaths.
- Complications like severe graft-versus-host disease and infections were noted, but overall, UCBT showed promise in stabilizing some patients' conditions, highlighting the need for more research and longer follow-up to fully understand its impact.
Vascular anomalies (VA) are developmental anomalies of veins, arteries, lymphatics or capillaries thought to be caused by mutations in genes that drive angiogenesis. Treatments targeting these genes are limited. We review the literature for conventional medications and products from traditional medicine cultures that have been found to have antiangiogenic activity.
View Article and Find Full Text PDFOutcomes of pediatric patients with therapy-related myeloid neoplasms.
Bone Marrow Transplant
December 2021
Long-term outcomes after allogeneic hematopoietic cell transplantation (HCT) for therapy-related myeloid neoplasms (tMNs) are dismal. There are few multicenter studies defining prognostic factors in pediatric patients with tMNs. We have accumulated the largest cohort of pediatric patients who have undergone HCT for a tMN to perform a multivariate analysis defining factors predictive of long-term survival.
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