Analysis of Socioeconomic Factors Affecting Follow-Up in a Glaucoma Screening Program.

Purpose: To determine what socioeconomic factors affect follow-up in a glaucoma screening program.

Patients And Methods: This was a retrospective cohort study of six health fairs in South Florida from October 2012 to March 2013 among socially and economically disadvantaged populations. Visual acuity (VA), intraocular pressure (IOP), cup-to-disc ratio (CDR), and visual field testing were obtained to identify glaucoma suspects.

Choroideremia Gene Therapy Phase 2 Clinical Trial: 24-Month Results.

Purpose: To report the final results of a phase 2 high-dose gene therapy clinical trial in choroideremia.

Methods: Design: Phase 2 clinical trial.

Participants: Six men (aged 32-72 years) with genetically-confirmed advanced choroideremia.

New Methods for Quantification of Visual Photosensitivity Threshold and Symptoms.

Purpose: Visual photosensitivity is a common symptom difficult to measure and diagnose, and is found in many ocular and neurological disorders. We developed two novel reproducible quantitative assessments of visual photosensitivity.

Methods: We designed and built the ocular photosensitivity analyzer (OPA), an automated instrument to determine light intensity visual photosensitivity threshold (VPT), and developed the Visual Light Sensitivity Questionnaire-8 (VLSQ-8), an eight-question survey to assess the presence and severity of photosensitivity symptoms.

Next-generation sequencing-based molecular diagnosis of 35 Hispanic retinitis pigmentosa probands.

Retinitis pigmentosa (RP) is a heterogeneous group of inherited retinal diseases. The prevalence of RP and the mutation spectrum vary across populations. Hispanic people account for approximately 17% of the United States population, and the genetic etiologies of RP of this ethnic group still remain not well defined.