Nesiritide improves hemodynamics in children with dilated cardiomyopathy: a pilot study.

Background: This study aimed to obtain hemodynamic measurements of nesiritide in children with dilated cardiomyopathy.

Methods: A prospective, randomized, double-blinded, placebo-controlled pilot study was conducted in the pediatric intensive care unit at the University of California, Los Angeles. All subjects younger than 21 years admitted to the pediatric intensive care unit with a diagnosis of dilated cardiomyopathy and submitted to cardiac catheterization were randomized to receive either nesiritide or placebo.